Evidence map›Paper›PMID 40128745›Full record

ArticleJournal of nanobiotechnology2025

In situ construction of heterojunctions to regulate the biodegradation behavior of copper carriers for tumor-specific cuproptosis-enhanced sono-immunotherapy.

Xiqian Cao, Lingwei Mao, Yijun Tian, Lang Yan, Bijiang Geng, Yingtang Zhou, Jiangbo Zhu

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiqian Cao *Department of Health Toxicology, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Lingwei Mao *Jiangsu University, Zhenjiang, Jiangsu Province, 212013, China.
Yijun Tian *Department of Health Toxicology, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Lang YanDepartment of Health Toxicology, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Bijiang GengSchool of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China. bjgeng1992@shu.edu.cn.
Yingtang ZhouNational Engineering Research Center for Marine Aquaculture, Zhejiang Ocean University, Zhoushan, Zhejiang Province, 316004, China. zhouyingtang@zjou.edu.cn.
Jiangbo ZhuDepartment of Health Toxicology, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China. jiangbozhu1@smmu.edu.cn.

Funding

National Natural Science Foundation of China 82173649
6 · The paper itself

Abstract

Cuproptosis, a novel approach utilizing copper carriers to trigger programmed cell death, exhibits promise for enhancing traditional therapies and activating robust adaptive immune responses. However, the uncontrolled release of Cu ions risks triggering cuproptosis in healthy tissues, potentially causing irreversible damage. To address this, we report on the use of a Cu-MOF (copper metal-organic framework) protective layer to regulate the biodegradation of copper-based nanomaterials. In situ formation of Cu-MOF on Cu

Indexed as

CopperImmunotherapyNeoplasmsUltrasonic TherapyAnimalsCell Line, TumorFemaleGlutathioneHumansMetal-Organic FrameworksMiceMice, Inbred BALB CNanostructuresReactive Oxygen SpeciesTumor MicroenvironmentCopperGlutathioneMetal-Organic FrameworksReactive Oxygen SpeciesChemodynamic therapyCu2OCuproptosisImmunotherapySonodynamic therapy

Identifiers

PMID40128745
PMCPMC11934600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.