Evidence map›Paper›PMID 40128743›Full record

ArticleBMC medicine2025

Association between urbanization levels and frailty among middle-aged and older adults in China: evidence from the CHARLS.

Xinlan Xie, Jiaqun Que, Linsu Sun, Tao Sun, Feng Yang

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Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  10. [Association between daytime napping and depressive symptoms in older women: The chain mediating role of frailty and C-reactive protein].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Xinlan Xie *Department of Cardiology, Renmin Hospital of Xiangzhou District, Xiangyang City, China.
Jiaqun Que *Department of Cardiology, Renmin Hospital of Xiangzhou District, Xiangyang City, China.
Linsu SunState Key Laboratory of New Drug Discovery and Development for Major Diseases, Gannan Medical University, Ganzhou, China.
Tao SunDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China. sunt1024@whu.edu.cn.
Feng YangDepartment of Cardiology, Renmin Hospital of Xiangzhou District, Xiangyang City, China. chuanfengyang@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid urbanization is underway in China. However, the impact of urbanization on frailty remains unclear. This study aims to investigate the relationship between urbanization and frailty among middle-aged and older adults.

methodsWe analyzed nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS) spanning 2011 to 2018. After applying inclusion and exclusion criteria, 10,758 non-frail individuals at baseline were analyzed. The exposure of interest was the comprehensive urbanization level. Urbanization level (0.072-0.689) was assessed using the entropy method. Frailty was assessed using the frailty index (FI), which ranges from 0 to 100. Frailty was defined as FI ≥ 25, and the urbanization-frailty association was assessed using - the restricted cubic spline (RCS) expressions and Cox proportional hazards models. Least absolute shrinkage and selection operator (LASSO) regression were employed to evaluate major factors associated with frailty.

resultsThe results revealed a U-shaped nonlinear association between urbanization level and frailty incidence, with a turning point at 0.3 (P

conclusionsUrbanization level had U-shaped association with frailty incidence. Factors such as total retail sales of consumer goods per capita, per capita disposable income of urban residents, and the number of college students per 10,000 people may be key in formulating a strategy for frailty prevention.

Indexed as

FrailtyUrbanizationAgedChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedProportional Hazards ModelsRisk FactorsCHARLSFrailtyIncidenceNonlinear relationshipUrbanization

Identifiers

PMID40128743
PMCPMC11934686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.