Evidence map›Paper›PMID 40128723›Full record

Observational studyBMC public health2025

Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination.

Renske Eilers, Fleur H Groenendijk, Birthe A Lehman, Nynke Y Rots, Hester E de Melker, Liesbeth Mollema, Josine van Beek

Abstract readObservational Study
In one paragraph

Observational study in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renske EilersCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Fleur H GroenendijkCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Birthe A LehmanCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Nynke Y RotsCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Hester E de MelkerCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Liesbeth MollemaCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Josine van BeekCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. josine.van.beek@rivm.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increase in the older adult population over the coming decades emphasizes the importance of vaccinations to prevent infectious diseases among this population. Acceptance of vaccination is crucial for a successful vaccination program and insight in the motives of acceptation is therefore important. This study explores specifically the association between experiencing influenza-like illness (ILI) and other determinants for older adults on seasonal influenza vaccination acceptance. Furthermore, differences in acceptance of pneumococcal, influenza, herpes zoster and pertussis vaccines between various age groups were studied.

methodsThree prospective observational studies (2011/2012, 2012/2013 and 2014/2015) were performed in community-dwelling older adults (≥ 60 years) to monitor ILI. During home visits, throat/nose swabs, a blood sample and a questionnaire on demographics and general health were collected. An additional questionnaire was added to the 2014/2015 study on motives and intention of older adults to accept seasonal influenza and other vaccinations, including knowledge statements on vaccination in general (n = 1647). Random Forest analyses were used to identify predictors of intention to accept seasonal influenza vaccination.

resultsUnivariate analyses showed that males, persons with limited contact with children, people who have received seasonal influenza vaccination in 2014/2015, persons reporting co-morbidity, persons reporting a lower perceived health and persons with more knowledge about vaccination have a significantly higher intention to accept seasonal influenza vaccination. The univariate and prediction analyses showed no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Previous influenza vaccination had by far the most predictive value; when excluding this factor, age and perceived health were the best predictors. Except for pertussis vaccination, persons aged ≥ 70 years had a higher intention to vaccinate compared to persons aged 60-69 years.

conclusionsOur study showed that there is no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Instead, previous influenza vaccination had the highest predictive value. Therefore, efforts should be made to make vaccination a habit to ensure annual vaccination. Healthcare workers, such as general practitioners (GPs) could play an important role in this because of frequent contact between older adults and GPs and the perceived importance of the advice of the GP.

trial registrationNTR4818 (30-09-2014).

Indexed as

Influenza, HumanInfluenza VaccinesIntentionPatient Acceptance of Health CareVaccinationAgedAged, 80 and overFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedProspective StudiesSeasonsSurveys and QuestionnairesInfluenza VaccinesDeterminantsInfluenza-like illnessInfluenza vaccinationVaccine acceptance

Identifiers

PMID40128723
PMCPMC11934534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.