Evidence map›Paper›PMID 40128482›Full record

ReviewAdvances in experimental medicine and biology2025

Recent Investigations Designed to Unravel the Interaction of Age and Alcohol on Behavior and Cognition: Potential Neurobiological Mechanisms.

Douglas B Matthews, Emily Kerr, Aeda Zank, Jadyn Hartwig, Averi Garscia, Samuel Stumo, Pravesh Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Douglas B MatthewsDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA. matthedb@uwec.edu.
Emily KerrDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA.
Aeda ZankDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA.
Jadyn HartwigDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA.
Averi GarsciaDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA.
Samuel StumoDepartment of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, USA.
Pravesh SharmaMayo Clinic Health System, Eau Claire, WI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding factors that alter the effect of alcohol in biological systems has been an area of active investigation for several decades. Recently, it has become clear that age is one of the most salient factors influencing how both acute and chronic alcohol exposure alters behavioral function. The following book chapter discusses how alcohol produces differential effects in adolescent animals in comparison to adult and aged (i.e., older) animals. Furthermore, where possible, relevant research identifying possible brain mechanisms mediating the differential effects of alcohol will be discussed. Finally, we highlight a small number of studies where sex and age of the subject interact to modify cognitive impairments produced by alcohol. We conclude that much work still needs to be done to fully understand how age, sex, and alcohol interact to produce the wide range of effects caused by consumption of the drug.

Indexed as

AgingAlcohol DrinkingBehavior, AnimalBrainCognitionEthanolAge FactorsAnimalsHumansEthanolAdolescentAgingAlcoholAlzheimer’s diseaseAtaxiaCognition

Identifiers

PMID40128482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.