Evidence map›Paper›PMID 40128474›Full record

ReviewAdvances in experimental medicine and biology2025

The Neurobiology of Learning and Memory in Rodent Models of Fetal Alcohol Spectrum Disorders.

Benjamin J Clark, Gabriela Acosta, Lilliana Sanchez, Kehiry Trejo Rico

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Assessment of GABANeuroscience letters · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin J ClarkDepartment of Psychology, University of New Mexico, Albuquerque, United States. bnjclark@unm.edu.
Gabriela AcostaDepartment of Psychology, University of New Mexico, Albuquerque, United States.
Lilliana SanchezDepartment of Psychology, University of New Mexico, Albuquerque, United States.
Kehiry Trejo RicoDepartment of Psychology, University of New Mexico, Albuquerque, United States.

Funding

Understanding neurophysiological deficits in response inhibition in children with FASDP50AA022534 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Carlos Fernando Valenzuela · 2014 to 2026
$21.5M
Alcohol and Developing Neuronal CircuitsR01AA015614 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Carlos Fernando Valenzuela · 2005 to 2026
$3.9M
Alcohol Research Training in NeurosciencesT32AA014127 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Jonathan L Brigman · 2003 to 2026
$3.3M
NIAAA NIH HHS P50 AA022534NIAAA NIH HHS R01 AA015614NIAAA NIH HHS T32 AA014127
6 · The paper itself

Abstract

Exposure to ethanol during gestation can lead to the onset of Fetal Alcohol Spectrum Disorders, which describes a range of neurodevelopmental and behavioral dysfunctions that include impairments in learning and memory and can have serious repercussions for scholastic performance during adolescence. The neurobiological basis of learning and memory dysfunction in Fetal Alcohol Spectrum Disorders has been frequently linked to the hippocampal formation, which is due in part to the fact that some hippocampal neurons, called place cells, fire action potentials correlated with an animal's spatial location as well as other features of memory episodes. The goal of this chapter is to provide an overview of research investigating developmental alcohol exposure in rodent models and the impact on learning and memory, hippocampal circuitry, and neural representations of learning and memory. We conclude by highlighting areas in which more concentrated behavioral and neurobiological study is needed to expand and develop rodent models of memory dysfunction in Fetal Alcohol Spectrum Disorders.

Indexed as

Fetal Alcohol Spectrum DisordersLearningMemoryMemory DisordersAnimalsDisease Models, AnimalEthanolFemaleHippocampusHumansPregnancyPrenatal Exposure Delayed EffectsRatsRodentiaEthanolExplorationFetal alcoholLearningMemoryObject memoryRodentSpatial

Identifiers

PMID40128474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.