Evidence map›Paper›PMID 40128423›Full record

ReviewDocumenta ophthalmologica. Advances in ophthalmology2025

Multi-channel pattern VEPs with full and half field stimulation: methods of interpretation and diagnostic evaluation.

Dorothy A Thompson, Oliver R Marmoy, Joanne Cowe, Siân E Handley

Abstract readReview
In one paragraph

Review in Documenta ophthalmologica. Advances in ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dorothy A ThompsonGreat Ormond Street Hospital for Children, NHS Foundation Trust, London, UK. dorothy.thompson@ucl.ac.uk.ORCID 0000-0001-5491-3911
Oliver R MarmoyGreat Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.ORCID 0000-0003-2022-3669
Joanne CoweGreat Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.ORCID 0009-0008-5499-4668
Siân E HandleyGreat Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.ORCID 0000-0002-7612-3889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe methods of evaluating multichannel full and half field pattern VEPs using the ISCEV VEP Standard montage.

methodsThe dependence of full field and half field pattern VEPs on retinal areas and cortical generators is reviewed and applied to the interpretation and evaluation of multichannel half field pattern VEPs.

resultsThere are predictable differences in the trans-occipital distributions of components of monocular full, and half field, pattern-reversal and full field, onset-offset VEPs. In combination, the differing distribution and dependence of these components on foveal and macular fields can help to identify and localise chiasmal and retro-chiasmal dysfunction and distinguish this from trans-occipital distribution due to individual variations of cortical architecture. A decision tree synthesising published evidence and current practice is suggested to guide interpretation of trans-occipital VEP distributions.

conclusionThe routine application of two additional lateral channels to acquire multichannel VEPs is quick, easy and adds clinical diagnostic value. The combination of full and half field pattern-reversal and fullfield, onset-offset VEPs can help evaluate chiasmal and retro-chiasmal visual pathway function, and minimise false positive interpretation of asymmetric VEP distributions, which may be due to cortical architecture or cranial anatomy alone.

Indexed as

Evoked Potentials, VisualVisual FieldsHumansPhotic StimulationVisual PathwaysChiasmHalf field stimulationHemifieldHemisphereMultichannel VEPParadoxical lateralisationPattern VEP

Identifiers

PMID40128423
PMCPMC11991936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.