Evidence map›Paper›PMID 40128414›Full record

ArticleBioresources and bioprocessing2025

Optimization of extraction process and solvent polarities to enhance the recovery of phytochemical compounds, nutritional content, and biofunctional properties of Mentha longifolia L. extracts.

Meryem Tourabi, Khaoula Faiz, Rachid Ezzouggari, Bouchra Louasté, Mohammed Merzouki, Musaab Dauelbait, Mohammed Bourhia, Khalid S Almaary, Farhan Siddique, Badiaa Lyoussi and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Bioresources and bioprocessing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  7. Formulation ofCurrent issues in molecular biology · 2026
    Article
  8. Review
  9. Phytochemistry and In Vitro Bioactivities ofMolecules (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Bioactive compounds fromFrontiers in pharmacology · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Antibiotics (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Meryem TourabiLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco. meryem.tourabi@usmba.ac.ma.
Khaoula FaizLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Rachid EzzouggariPhytopathology Unit, Department of Plant Protection, Ecole Nationale d'Agriculture de Meknès, Km10, Rte Haj Kaddour, BP S/40, 50001, Meknès, Morocco.
Bouchra LouastéLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Mohammed MerzoukiLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Musaab DauelbaitUniversity of Bahr el Ghazal, Freedowm Stree, Wau, 91113, South Sudan. musaabelnaim@gmail.com.
Mohammed BourhiaLaboratory of Biotechnology and Natural Resources Valorization, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco.
Khalid S AlmaaryDepartment of Botany and Microbiology, College of Science, King Saud University, P. O. BOX 2455, 11451, Riyadh, Saudi Arabia.
Farhan SiddiqueSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, People's Republic of China.
Badiaa LyoussiLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Elhoussine DerwichLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study attempted to evaluate the influence of three extraction processes such as Soxhlet, ultrasound-assisted extraction (UAE,) and cold maceration on one hand and solvent polarities (ethanol 70%, ethyl acetate, and water) on the other hand, vs. phytoconstituents and biofunctional properties of Mentha longifolia L. Noteworthy, all extracts were examined in terms of their chemical components, phenolic and flavonoid content, antioxidant and antimicrobial potentials. Notably, high-performance liquid chromatography coupled with array detector analysis (HPLC-DAD) showed the existence of many phenolic compounds. Hydro-ethanol extract (ETOH 70% (v/v)) prepared with maceration and Soxhlet process showed the ultimate rate of phenolic compounds coupled with the most powerful antioxidant and antimicrobial capacity. Notably, ETOH extract obtained with UAE showed important nutritional properties, particularly soluble carbohydrate (50.1 ± 0.70 mg/g dry weight), and soluble protein (26.5 ± 0.5 mg/g dry weight), while aqueous extract obtained by use of UAE extraction maximized pigment content. The outcome of this work showed that Soxhlet and maceration extraction processes with many polar solvents are more appropriate for M. longifolia extraction. M. longifolia possesses promising phytochemicals, which can be used in different sectors like food, pharmaceutical, and cosmetic formulations.

Indexed as

Antimicrobial potentialAntioxidant capacityBioactive preservativeExtraction processHPLC–DADMentha longifoliaPolyphenolsSolvent polarities

Identifiers

PMID40128414
PMCPMC11933538

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.