Evidence map›Paper›PMID 40128329›Full record

ArticleCardiovascular and interventional radiology2025

Transcatheter Arterial Embolization as a Treatment for Chronic Pain due to Osteoarthritis.

Florian Nima Fleckenstein, Jan Voss, Christian Doll, Tazio Maleitzke, Tobias Winkler, Eberhard Siebert, Federico Collettini

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Florian Nima FleckensteinDepartment of Diagnostic and Interventional Radiology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. florian.fleckenstein@charite.de.ORCID http://orcid.org/0000-0003-1088-1721
Jan VossBerlin Institute of Health at Charité Universitätsmedizin, Berlin, Germany.
Christian DollDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Tazio MaleitzkeCenter for Musculoskeletal Surgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Tobias WinklerBerlin Institute of Health at Charité Universitätsmedizin, Berlin, Germany.
Eberhard SiebertInstitute of Neuroradiology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Federico Collettini *Department of Diagnostic and Interventional Radiology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the efficacy and safety of transarterial embolization (TAE) for the treatment of temporomandibular joint osteoarthritis (TMJ-OA)-related symptoms. MATERIALS AND

methodsThree female patients were referred to our center for TAE after conservative and surgical TMJ treatments failed. Six TAE procedures were performed with bilateral treatments spaced four weeks apart. Following CBCT with maximal magnification and narrow collimation to confirm correct positioning of the microcatheter, superselective TAE was performed using Imipenem/Cilastatin mixed with contrast medium. Technical success was defined by successful embolization of the target vessel. Outcome measures included Oral Health Impact Profile-Temporomandibular Joint (OHIP-TMD) and Numeric Rating Scale (NRS) at baseline, 4 weeks and at 3 months intervals.

resultsTAE was technically successful in all six procedures. No adverse events were recorded. Clinical follow-up data after 3 months are available for all three patients, one patient reached the 6-months follow-up. OHIP-TMD scores decreased from 38 to 31, 45 to 39, and 45 to 28, respectively. NRS pain scores improved from 9 to 6, 10 to 7, and 9 to 5, respectively.

conclusionTAE appears to be a feasible and safe minimally-invasive option for selected TMJ-OA patients with symptoms refractory to standard treatments. Further studies with larger cohorts and extended follow-up are warranted to confirm these preliminary findings.

Indexed as

Chronic PainEmbolization, TherapeuticOsteoarthritisTemporomandibular Joint DisordersAdultCone-Beam Computed TomographyContrast MediaFemaleHumansMiddle AgedPain MeasurementTreatment OutcomeContrast MediaInterventional RadiologyMusculoskeletal DiseasesOsteoarthritisPain ManagementTemporomandibular Joint

Identifiers

PMID40128329
PMCPMC12053019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.