Evidence map›Paper›PMID 40128217›Full record

ArticleNPJ science of food2025

Portable DNA extraction integrated with LAMP-CRISPR/Cas12a technology for on-site detection of Salmonella Typhimurium.

Liang Zhang, Mengfan Zhang, Xingxing Liu, Jia Wei, Caihong Yin, Nan Wang, Beibei Fan, Yanli Fu, Yanwen Liu, Liangyun Bu and 4 more

Abstract read
In one paragraph

Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Liang ZhangSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Mengfan ZhangSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Xingxing LiuDepartment of Cadre Ward, The First Hospital of Jilin University, 130021, Changchun, P.R. China.
Jia WeiDepartment of Thyroid Surgery, General Surgery Center, The First Hospital of Jilin University, 130021, Changchun, P.R. China.
Caihong YinSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Nan WangSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Beibei FanSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Yanli FuSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Yanwen LiuSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Liangyun BuSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Zhenyue SuSchool of Public Health, Jilin University, 130021, Changchun, P.R. China.
Bo PangSchool of Public Health, Jilin University, 130021, Changchun, P.R. China. bopang1@jlu.edu.cn.
Jinhua LiSchool of Public Health, Jilin University, 130021, Changchun, P.R. China. jinhua1@jlu.edu.cn.
Xiuling SongSchool of Public Health, Jilin University, 130021, Changchun, P.R. China. songxiuling@jlu.edu.cn.

Funding

Jilin University (JLU) 2022JBGS09National Natural Science Foundation of China (National Science Foundation of China) 82103892National Natural Science Foundation of China (National Science Foundation of China) 82373578
6 · The paper itself

Abstract

The infection and outbreak of Salmonella typhimurium (S. typhimurium) highlight the need for developing a reliable on-site detection strategy fitting to various settings. However, due to the requirement of specialized instruments and trained personnel, traditional detection methods have to be implemented in laboratories and are not ideal for on-site applications. To achieve a sample-to-answer and field-deployable detection for S. typhimurium, we developed an integrated nucleic acid detection platform combining single-vial of loop-mediated isothermal amplification (LAMP)-clustered regularly interspaced short palindromic repeat (CRISPR)/Cas12a system, portable device and smartphone app. This platform enables the extraction, concentration, and purification of DNA, amplification of the target, and output of visual fluorescent signals within 1 h. With this detection platform, 10

Identifiers

PMID40128217
PMCPMC11933393

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.