Evidence map›Paper›PMID 40128090›Full record

Observational studyNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2025

A novel system to continuously estimate intradialytic blood pressure in real time.

Daniela Viramontes-Hörner, Paul Stewart, Jill Stewart, Maarten W Taal, Nicholas M Selby

Abstract readObservational Study
In one paragraph

Observational study in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela Viramontes-HörnerCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Derby, UK.ORCID 0000-0002-4861-623X
Paul StewartCollege of Science and Engineering, University of Derby, Derby, UK.
Jill StewartInstitute of Engineering, Computing and Advanced Manufacturing, University of Cumbria, Carlisle, UK.
Maarten W TaalCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Derby, UK.ORCID 0000-0002-9065-212X
Nicholas M SelbyCentre for Kidney Research and Innovation, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Derby, UK.ORCID 0000-0003-0351-8326

Funding

Kidney Research UK Charities KS_RP_005_20210111MSTART
6 · The paper itself

Abstract

backgroundIntradialytic hypotension (IDH) is a common complication of haemodialysis that is associated with adverse patient outcomes. We have developed a new non-invasive approach to continuously estimate systolic blood pressure (SBP) in real time during haemodialysis using pressure wave sensors in the extracorporeal circuit. We sought to compare the performance of our continuous real-time SBP estimator against brachial cuff SBP measurements.

methodsSingle-centre, observational study conducted in 21 participants receiving haemodialysis with a functioning arteriovenous fistula, studied throughout two 4-h haemodialysis sessions. Time-averaged real-time SBP estimator values from the 5-s period immediately prior to each cuff measurement were compared with matched brachial cuff SBP values.

resultsMean age was 71 ± 11 years and median dialysis vintage was 20.0 months (interquartile range 12.5-63.5). Across 522 SBP comparison data points, mean brachial cuff SBP and real-time SBP estimate were 121.8 ± 27.1 mmHg and 123.7 ± 27.9 mmHg, respectively. Brachial cuff SBP and real-time SBP estimate were significantly associated (r = 0.825; P < .001). There was a low absolute mean difference between the brachial cuff SBP and the real-time SBP estimate of -1.9 ± 16 mmHg, and no evidence of systematic bias between measurements. Across all comparison points, 95% of estimator values were within 30% of the matched brachial cuff value, and 66% within 10% of the cuff value.

conclusionsA blood pressure estimator that runs in real time during haemodialysis using pressure wave sensors in the extracorporeal circuit and avoiding additional sensor-burden on patients has good performance in tracking intradialytic SBP when compared against brachial cuff measurements, supporting its further development and larger scale testing.

Indexed as

Blood PressureBlood Pressure DeterminationHypotensionKidney Failure, ChronicRenal DialysisAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisarterial pulse wavecontinuous blood pressurehaemodialysisintradialytic hypotensionsystolic blood pressure

Identifiers

PMID40128090
PMCPMC12620638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.