Evidence map›Paper›PMID 40128066›Full record

Observational studyMedicine2025

Prediction of medication nonadherence in patients with lung cancer based on nomogram model construction.

Jiuli Hu, Chanchan Hu, Yunwei Liang, Ziwei Wang, Yunfei Liang, Jiying Ma, Ying Wang

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiuli HuDepartment of Pharmacy, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.
Chanchan HuDepartment of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.
Yunwei LiangDepartment of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.
Ziwei WangDepartment of Pharmacy, Staff Hospital of Chengde Iron and Steel Group Co., Ltd., Chengde, Hebei, PR.
Yunfei LiangDepartment of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.
Jiying MaDepartment of Pneumology, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.
Ying WangDepartment of Pharmacy, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, PR China.ORCID 0000-0002-3463-5667

Funding

the the S&T Program of Chengde 202406A024
6 · The paper itself

Abstract

Lung cancer is the leading cause of death among patients with cancer. Medication nonadherence affects survival time and remission of disease symptoms in patients with lung cancer. Therefore, this study analyzed the risk factors for medication nonadherence in patients with lung cancer and established a nomogram prediction model. The basic information and clinical characteristics of patients with lung cancer were collected from the Affiliated Hospital of Chengde Medical University from April 2020 to March 2023. The Chinese version of the Morisky Medication Adherence Questionnaire-8 was used to evaluate patients' medication adherence. A least absolute shrinkage and selection operator regression model and multivariate logistic regression analysis were used to identify the risk factors for medication nonadherence and establish a nomogram prediction model. The predictive ability of the nomogram was evaluated using the concordance index (C-index) and the area under the operating characteristic curve. Decision curve analysis (DCA) and the clinical impact curve were used to assess the potential clinical value of the nomogram. A total of 161 patients with lung cancer were included in this study, with a medication nonadherence rate of 47.20%. Risk factors included age, surgery, education level, bone metastases, comorbidities, well-being, and constipation. The C-index and area under the operating characteristic curve were 0.946. The threshold probability for DCA ranged from 0.07 to 0.95. The nomogram can predict the risk of medication nonadherence in patients with lung cancer and help identify those at risk early in clinical settings, allowing for the development of intervention programs and improved clinical management.

Indexed as

Lung NeoplasmsNomogramsAdultAgedChinaFemaleHumansMaleMiddle AgedRisk FactorsSurveys and Questionnaires

Identifiers

PMID40128066
PMCPMC11936642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.