Evidence map›Paper›PMID 40127908›Full record

ArticleJournal of epidemiology and community health2025

Prevalence of maternal substance use problems during pregnancy and the first 2 years of life: a whole-population birth cohort of 970 470 Australian children born 2008-2017.

Madeleine Powell, Rhiannon Pilkington, Tasnia Ahmed, Mark Hanly, B J Newton, John W Lynch, Timothy Dobbins, Jessica Stewart, Michelle Cretikos, Alys Havard and 1 more

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Substance and alcohol use in pregnant women attending antenatal care at a tertiary hospital in Johannesburg, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Madeleine PowellSchool of Population Health, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia madeleine.powell@unsw.edu.au.ORCID http://orcid.org/0000-0002-2992-9900
Rhiannon PilkingtonSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0001-6974-8496
Tasnia AhmedSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Mark HanlyCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.
B J NewtonSocial Policy Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
John W LynchSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.
Timothy DobbinsSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Jessica StewartFamily and Community Services Insights, Analysis and Research, NSW Department of Communities and Justice, Sydney, New South Wales, Australia.
Michelle CretikosCentre for Epidemiology and Evidence, Ministry of Health, Sydney, New South Wales, Australia.
Alys HavardSchool of Population Health, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
Kathleen FalsterSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-2035-5485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the prevalence of maternal substance use problems during the first 1000 days of children's lives, to inform planning and resourcing of antenatal screening and substance use in pregnancy services, alongside antenatal and postnatal health, parenting and social support services for pregnant women/new mothers and their babies.

methodThis whole-population cohort was assembled from birth registration, perinatal and hospital data for children born 2008-2017, and their mothers, using data linked for the New South Wales (NSW) Child E-Cohort Project. The primary outcome was maternal substance use conditions and treatment recorded in six health, death and child protection data sources from the child's conception to age 2 years (the first 1000 days), including illicit substances, alcohol, opioid-agonist treatment and misuse of psychoactive medicines or substances.

resultsOf 970 470 children born to 625 856 mothers, 3.4% (N=32 647) had ≥1 maternal substance use problem records in the first 1000 days, including alcohol use (N=13 637; 1.4%) and other drug use (N=23 485; 2.4%). Maternal substance use problems were recorded during the pregnancy period for 1.4% of children, and from 28 to 1000 days postbirth for 2.7% of children. Outcome ascertainment was highest from child protection records (N=26 045), followed by mother's (N=10 793) then children's hospital records (N=3827). Child protection records more than doubled the prevalence of health and death records alone (1.4%). Social and health disadvantage was more common among children with maternal substance use problems.

conclusionsDuring the first 1000 days of life, 3.4% of NSW children had ≥1 maternal substance use problem recorded in health, child protection and death data sources. Child protection data enhance public health intelligence on the burden of maternal substance use problems among whole child populations. Near universal health system contact during pregnancy and birth is an opportunity to initiate early support for maternal substance use and co-occurring health and social disadvantage, to promote child health and development.

Indexed as

MothersPregnancy ComplicationsSubstance-Related DisordersAdultAustraliaBirth CohortChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMaleNew South WalesPregnancyPrevalenceCHILD HEALTHEPIDEMIOLOGYMATERNAL HEALTHPREVENTIONSUBSTANCE ABUSE

Identifiers

PMID40127908
PMCPMC12322432

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.