Evidence map›Paper›PMID 40127662›Full record

ReviewThe Lancet. Respiratory medicine2025

Post-tuberculosis lung disease: towards prevention, diagnosis, and care.

Jamilah Meghji, Sara C Auld, Gregory P Bisson, Celso Khosa, Refiloe Masekela, Neelima Navuluri, Andrea Rachow

Abstract readReview
In one paragraph

Review in The Lancet. Respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Asthma Incidence and Risk Factors in Tuberculosis Survivors: A Longitudinal Analysis of National Health Data.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Tuberculosis: So much accomplished and so much more to be done.The Indian journal of medical research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jamilah MeghjiNational Heart & Lung Institute, Imperial College London, London, UK; Department of Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK. Electronic address: j.meghji@imperial.ac.uk.
Sara C AuldDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Department of Epidemiology and Department of Global Health, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Gregory P BissonDepartment of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Celso KhosaInstituto Nacional de Saúde, Marracuene, Mozambique; Department of Physiological Science, Clinical Pharmacology, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Refiloe MasekelaDepartment of Paediatrics and Child Health, College of Health Sciences, School of Clinical Medicine, University of KwaZulu Natal, Durban, South Africa; Africa Health Research Institute, Durban, South Africa.
Neelima NavuluriDepartment of Medicine, Division of Pulmonary and Critical Care, Duke University School of Medicine, Durham, NC, USA; Duke Global Health Institute, Duke University, Durham, NC, USA.
Andrea RachowInstitute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Germany; German Centre for Infection Research (DZIF), Munich, Germany; Unit of Global Health, Helmholtz Centre Munich, German Research Centre for Environmental Health (HMGU), Neuherberg, Germany.

Funding

Emory/Georgia TB Research Advancement Center (TRAC)P30AI168386 · NIAID · EMORY UNIVERSITY · PI Jeffrey M Collins · 2022 to 2026
$5.8M
Inflammation and Fibrosis in Pulmonary TB: the INFIN-TB StudyR01AI166988 · NIAID · EMORY UNIVERSITY · PI Sara Auld, GREGORY P. BISSON · 2022 to 2026
$5.1M
Department of Health NIHR156700NIAID NIH HHS P30 AI168386NIAID NIH HHS R01 AI166988
6 · The paper itself

Abstract

There is a growing body of data describing the high burden of respiratory sequelae seen among tuberculosis survivors, including children, adolescents, and adults. This group of sequelae are known as post-tuberculosis lung disease and include parenchymal damage, airway disease, and pulmonary vascular disease. It is thought that approximately half of pulmonary tuberculosis survivors have ongoing structural pathology, lung function impairment, or respiratory symptoms after the resolution of active disease. Post-tuberculosis lung disease has been associated with adverse patient outcomes, including persistent symptoms and functional impairment, ongoing health seeking, and impacts on income and employment. There is still much to understand about the epidemiology and nature of post-tuberculosis lung disease, but in this Review we focus on strategies for prevention, diagnosis, and care to inform the ongoing work of tuberculosis-affected communities, health-care providers, researchers, and policy makers. We summarise recent data, highlight evidence gaps, and suggest key research priorities for those working in the field.

Indexed as

Lung DiseasesTuberculosis, PulmonaryAdultChildHumansSurvivors

Identifiers

PMID40127662
PMCPMC7618543

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.