Evidence map›Paper›PMID 40127382›Full record

ArticleJCO global oncology2025

Quality of Care and Survival Outcomes Among Patients With Clinically Localized Prostate Cancer in Nigeria.

Musliu Adetola Tolani, Christian Agbo Agbo, Alan Paciorek, Shehu Salihu Umar, Rufus Wale Ojewola, Faruk Mohammed, Ernie Kaninjing, Muhammed Ahmed, Rebecca DeBoer

Abstract read
In one paragraph

Article in JCO global oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Prostate Cancer Management in Nigeria: A mini-review of up-to-date treatment options.Nigerian medical journal : journal of the Nigeria Medical Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Musliu Adetola TolaniAhmadu Bello University Teaching Hospital, Ahmadu Bello University, Zaria, Nigeria.ORCID 0000-0003-4296-9744
Christian Agbo AgboBenue State University Teaching Hospital, Makurdi, Nigeria.ORCID 0000-0001-5889-309X
Alan PaciorekUniversity of California, San Francisco, CA.ORCID 0000-0003-3900-882X
Shehu Salihu UmarAhmadu Bello University Teaching Hospital, Ahmadu Bello University, Zaria, Nigeria.
Rufus Wale OjewolaLagos University Teaching Hospital, University of Lagos, Idi-Araba, Nigeria.
Faruk MohammedAhmadu Bello University Teaching Hospital, Ahmadu Bello University, Zaria, Nigeria.ORCID 0000-0003-2319-8948
Ernie KaninjingGeorgia College and State University, Milledgeville, GA.ORCID 0000-0003-4250-9756
Muhammed AhmedAhmadu Bello University Teaching Hospital, Ahmadu Bello University, Zaria, Nigeria.ORCID 0000-0003-4657-6702
Rebecca DeBoerUniversity of California, San Francisco, CA.ORCID 0000-0001-8083-1290

Funding

Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alan Ashworth · 1999 to 2026
$209.7M
NCI NIH HHS P30 CA082103
6 · The paper itself

Abstract

purposeOptimal survival outcomes of prostate cancer are best achieved through high-quality care for curable disease. In Nigeria, various barriers may impede the curative treatment of prostate cancer, yet their impact on care and patient outcomes remains anecdotal. This study assessed treatment quality, survival outcomes, and interhospital differences of these metrics among patients with clinically localized prostate cancer in Nigeria.

methodsA retrospective study of patients with clinical stage T1-T3a, M0 prostate cancer at three tertiary hospitals in Nigeria over a 3-year period was conducted. Data on hospital sites, sociodemographics, clinicopathologic characteristics, quality metrics, imaging used, treatment, and survival status were collected. The primary end point was time from diagnosis to first treatment. Secondary end points were time from presentation to diagnosis, other prostate cancer quality metrics, all-cause survival, and interhospital differences in these metrics. Quality of diagnostics, treatments, and other outcomes were described and compared using Cox regression.

resultsThis study included 110 patients with a median age of 67 years. Most (n = 66, 61%) had high-risk disease. The median time from tertiary hospital presentation to diagnosis was 31 days. Median time from diagnosis to first treatment of any type was 68 days, with radical radiotherapy was 117 days, and with radical prostatectomy was 104 days. Eighteen percent (n = 20) had guideline-concordant imaging for tumor staging, 67 patients (61%) received any treatment or active surveillance, and retention in care was 42%. Three-year all-cause survival was 41%. There was a significant difference in most quality metrics including guideline-concordant imaging and treatment across the hospital sites.

conclusionTime to treatment was delayed beyond international benchmarks; quality of staging, treatment, and care process were suboptimal; and survival was poor amid geographical disparities in care.

Indexed as

Prostatic NeoplasmsQuality of Health CareAgedAged, 80 and overHumansMaleMiddle AgedNeoplasm StagingNigeriaRetrospective StudiesTreatment Outcome

Identifiers

PMID40127382
PMCPMC12004982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.