Evidence map›Paper›PMID 40126936›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies.

Tamir Avigdor, Guoping Ren, Chifaou Abdallah, François Dubeau, Christophe Grova, Birgit Frauscher

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tamir AvigdorAnalytical Neurophysiology Lab, McGill University, Montreal, QC, H3A 2B4, Canada.ORCID https://orcid.org/0000-0003-1283-7978
Guoping RenDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
Chifaou AbdallahAnalytical Neurophysiology Lab, McGill University, Montreal, QC, H3A 2B4, Canada.
François DubeauMontreal Neurological Institute and Hospital, McGill University, Montreal, QC, H3A 2B4, Canada.
Christophe GrovaMultimodal Functional Imaging Lab, Biomedical Engineering Department, McGill University, Montreal, QC, H3A 2B4, Canada.
Birgit FrauscherAnalytical Neurophysiology Lab, McGill University, Montreal, QC, H3A 2B4, Canada.ORCID https://orcid.org/0000-0001-6064-1529

Funding

CIHR PJT 159948CIHR PJT-175056
6 · The paper itself

Abstract

Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo-electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of the process of awakening at a local level 15 min before and after the awakening. Awakenings from non-rapid eye movement sleep are accompanied by a widespread increase in ripple (>80 Hz) power in the fronto-temporal and parieto-insular regions, with connectivity showing an almost exclusive increase in the ripple band in the somatomotor, default, dorsal attention, and frontoparietal networks. Awakenings from rapid eye movement sleep are characterized by a widespread and almost exclusive increase in the ripple band in all available brain lobes, and connectivity increases mainly in the low ripple band in the limbic system as well as the default, dorsal attention, somatomotor, and frontoparietal networks.

Indexed as

BrainWakefulnessAdultElectroencephalographyFemaleHumansMaleMiddle AgedPolysomnographyawakeningconnectivityintracranial EEGsleepspectral analysis

Identifiers

PMID40126936
PMCPMC12097024

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.