Evidence map›Paper›PMID 40126910›Full record

ArticleSexually transmitted diseases2025

STI Testing and Rates of STI Diagnoses Before and During the COVID-19 Pandemic in a US HIV Cohort.

Gina M Simoncini, Carl Armon, Kate Buchacz, Jonathan Mahnken, Qingjiang Hou, Kalliope Chagaris, Jack Fuhrer, Cynthia Mayer, Cynthia Firnhaber, Marcus D Durham and 4 more

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gina M SimonciniFrom the AbsoluteCare, Philadelphia, PA.
Carl ArmonCerner Corporation, Kansas City MO.
Kate BuchaczCenters for Disease Control and Prevention, Atlanta, GA.
Jonathan MahnkenCerner Corporation, Kansas City MO.
Qingjiang HouCerner Corporation, Kansas City MO.
Kalliope ChagarisCerner Corporation, Kansas City MO.
Jack FuhrerStony Brook Medicine, Stony Brook, NY.
Cynthia MayerSt. Josephs Comprehensive Research Institute, Tampa, FL.
Cynthia FirnhaberVivent Health, Denver.
Marcus D DurhamCenters for Disease Control and Prevention, Atlanta, GA.
Alexander C EwingCenters for Disease Control and Prevention, Atlanta, GA.
Kimberly CarlsonCerner Corporation, Kansas City MO.ORCID 0000-0003-2022-8750
Jun LiCenters for Disease Control and Prevention, Atlanta, GA.
HIV Outpatient Study (HOPS) Investigators

Funding

CDC HHS 200-2001-00133CDC HHS 200-2006-18797CDC HHS 200-2011-41872CDC HHS 200-2015-63931CDC HHS 75D30120C08752
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic affected sexually transmitted infection (STI) testing and diagnosis rates in the United States, but these patterns have not been well characterized among people with HIV.

methodsWe analyzed medical records data of HIV Outpatient Study (HOPS) participants seen for HIV care from January 2019 to March 2021, with ≥1 CD4+ cell count and viral load test results recorded. We used Poisson regression models to estimate rate ratio (RR) and 95% confidence interval (CI) to compare STI testing and diagnoses rates on/after versus before March 1, 2020 (early COVID-19 pandemic [pandemic] vs. prepandemic).

resultsOf 2311 eligible patients, STI tests (STI cases, primarily defined as test results that were positive) were as follows during the analysis time frame: 4991 gonorrhea (157), 4978 chlamydia (135), and 4216 syphilis (114). Comparing pandemic versus prepandemic periods, STI testing RRs were 0.78 for both gonorrhea (95% CI, 0.73-0.82) and chlamydia (95% CI, 0.73-0.83), and 0.93 for syphilis (95% CI, 0.88-0.99); diagnosis rates were not statistically different. Multivariable models showed reduced testing for gonorrhea (adjusted RR, 0.79; 95% CI, 0.72-0.87) and chlamydia (adjusted RR, 0.78; 95% CI, 0.71-0.86) for men who have sex with men, but not for other HIV transmission groups.

conclusionsThe fallout of the COVID-19 pandemic on sexual health may not be seen for some time. Despite reduced STI testing, rates of STI diagnoses did not decrease. It will take a return to more routine screening and improved access to sexual health care to uncover the true impact of undetected or untreated STIs.

Indexed as

COVID-19HIV InfectionsSexually Transmitted DiseasesAdultChlamydia InfectionsCohort StudiesFemaleGonorrheaHumansMaleMass ScreeningMiddle AgedPandemicsSARS-CoV-2SyphilisUnited States

Identifiers

PMID40126910
PMCPMC12180713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.