Evidence map›Paper›PMID 40126780›Full record

ArticleMagma (New York, N.Y.)2025

Synthetic DWI: contrast improvement for diffusion-weighted imaging in prostate using T1 shine-through by synthesizing images with adjusted TR and TE.

Yu Ueda, Tsutomu Tamada, Atsushi Higaki, Ayumu Kido, Hiroyasu Sanai, Kazunori Moriya, Taro Takahara, Makoto Obara, Marc Van Cauteren

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prostate Diffusion-weighted Imaging: Selecting the Optimal Repetition Time Using Synthetic Imaging Techniques.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu UedaPhilips Japan, Azabudai Hills Mori JP Tower 15F, 1-3-1 Azabudai, Minato-ku, Tokyo, 106-0041, Japan. yu.ueda@philips.com.ORCID http://orcid.org/0000-0002-7742-6259
Tsutomu TamadaDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.
Atsushi HigakiDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.
Ayumu KidoDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.
Hiroyasu SanaiDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.
Kazunori MoriyaDepartment of Radiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.
Taro TakaharaDepartment of Biomedical Engineering, Tokai University School of Engineering, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Makoto ObaraPhilips Japan, Azabudai Hills Mori JP Tower 15F, 1-3-1 Azabudai, Minato-ku, Tokyo, 106-0041, Japan.
Marc Van CauterenPhilips Japan, Azabudai Hills Mori JP Tower 15F, 1-3-1 Azabudai, Minato-ku, Tokyo, 106-0041, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether synthetic DWI (SyDWI) calculated with short TR and zero TE can improve diffusion contrast in prostate compared to conventional DWI acquired with standard TR and TE. MATERIALS AND

methodsThirty-two patients who underwent multiparametric MRI (mp-MRI) on a 3.0 T scanner were enrolled. For SyDWI, DWIs at b0 were acquired with two different TRs and TEs in addition to b1000 and b2000 images acquired with single conventional TR and TE. Contrast ratio (CR) was compared between SyDWI calculated with TR of 1000 ms and TE of 0 ms and conventional DWI acquired with TR of 6000 ms and TE of 70 ms.

resultsThe mean CR between prostate cancer (PCa) and normal prostate, and between PCa and benign prostatic hyperplasia (BPH), is significantly higher in SyDWI compared to conventional DWI for both b-values of 1000 and 2000 s/mm

conclusionSyDWI calculated with TR of 1000 ms and TE of 0 ms significantly improves diffusion contrast between PCa and normal prostate or BPH, and within the lesion, compared to conventional DWI as a result of T1 shine-through.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedProstateProstatic NeoplasmsAgedAged, 80 and overContrast MediaHumansImage Interpretation, Computer-AssistedMaleMiddle AgedMultiparametric Magnetic Resonance ImagingProstatic HyperplasiaReproducibility of ResultsContrast MediaDiffusion-weighted imagingImage synthesisProstateT1 shine-throughT2 shine-through

Identifiers

PMID40126780

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.