Evidence map›Paper›PMID 40126759›Full record

ArticleInternal and emergency medicine2025

A challenging diagnosis of malignant peritoneal mesothelioma.

Marco Soncini, Mishel Malethi Wanasinghe Arachchige, Chiara Frigerio, Lara Verdi, Ruben Bordoli

Abstract readCase Reports
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In one paragraph

Article in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco SonciniDepartment of Internal Medicine, Hospital A. Manzoni, via Dell'Eremo, 9/11, 23900, Lecco, Italy. marco.soncini1@gmail.com.ORCID 0000-0002-2745-1560
Mishel Malethi Wanasinghe ArachchigeDepartment of Medicine and Surgery, Clinica Medica, University of Milano-Bicocca, via Pergolesi 33, 20052, Monza, Milan, Italy.
Chiara FrigerioDepartment of Internal Medicine, Hospital A. Manzoni, via Dell'Eremo, 9/11, 23900, Lecco, Italy.
Lara VerdiDepartment of Internal Medicine, Hospital A. Manzoni, via Dell'Eremo, 9/11, 23900, Lecco, Italy.
Ruben BordoliDepartment of Internal Medicine, Hospital A. Manzoni, via Dell'Eremo, 9/11, 23900, Lecco, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant Peritoneal Mesothelioma (MPM) is a rare and aggressive cancer originating in the mesothelial serosal membranes, often associated with pleural mesothelioma. Its diagnosis is challenging due to its nonspecific symptoms, such as abdominal distension, pain, weight loss, and ascites, which overlap with other abdominal conditions. This case study details a 64-year-old male patient with a complex clinical presentation, initially misdiagnosed with seronegative celiac disease, before ultimately being diagnosed with MPM through video-laparoscopy. Despite extensive workup-including CT, PET scans, and colonoscopy-the diagnosis was delayed until peritoneal nodules were identified. MPM remains difficult to detect, often identified at advanced stages, with a poor prognosis and a median survival of less than 1 year post-diagnosis. This case underscores the importance of a comprehensive diagnostic approach, particularly in patients with nonspecific abdominal symptoms, to improve early detection and treatment outcomes for MPM.

Indexed as

Lung NeoplasmsMesotheliomaPeritoneal NeoplasmsHumansMaleMesothelioma, MalignantMiddle AgedTomography, X-Ray ComputedMalignant peritoneal mesothelioma (MPM)ParacentesisSerum-to-ascites albumin gradient (SAAG)Video-laparoscopic surgery

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.