Evidence map›Paper›PMID 40126605›Full record

ArticleEuropean radiology2025

Assessment of proximal tibial fractures with 3D FRACTURE (fast field echo resembling a CT using restricted echo-spacing) MRI-intra-individual comparison with CT.

Inka Ristow, Shuo Zhang, Christoph Riedel, Alexander Lenz, Ralph Akoto, Matthias Krause, Gerhard Adam, Peter Bannas, Frank Oliver Henes, Lennart Well

Abstract readComparative Study
In one paragraph

Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Inka RistowDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. i.ristow@uke.de.ORCID http://orcid.org/0000-0002-3032-2321
Shuo ZhangPhilips, Best, The Netherlands.ORCID http://orcid.org/0000-0002-1057-7255
Christoph RiedelDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-8342-296X
Alexander LenzDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0003-1916-1317
Ralph AkotoDepartment of Trauma Surgery, Orthopaedics and Sports Traumatology, BG Hospital Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-5470-4981
Matthias KrauseDepartment of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-7345-6506
Gerhard AdamDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-7976-3868
Peter BannasDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-7102-534X
Frank Oliver HenesDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-5639-692X
Lennart WellDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2491-1346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the feasibility and diagnostic performance of a 3D FRACTURE (fast field echo resembling a CT using restricted echo-spacing) MRI sequence for the detection and classification of proximal tibial fractures compared with CT.

methodsWe retrospectively included 126 patients (85 male; 39.6 ± 14.5 years) from two centers following acute knee injury. Patients underwent knee MRI at 3 T including FRACTURE-MRI. Additional CT was performed in patients with tibial fractures (32.5%; n = 41) as the reference standard for fracture classification. Two radiologists independently evaluated FRACTURE-MRI for the presence of fractures and classified them according to AO/OTA, Schatzker, and the 10-segment classification. Diagnostic performance of FRACTURE-MRI was assessed using crosstabulations. Inter-reader agreement was estimated using Krippendorff's alpha. Image quality was graded on a five-point scale (5 = excellent; 1 = inadequate definition of fracture lines and fracture displacement) and assessed using estimated marginal means.

resultsFractures were detected by FRACTURE-MRI with a sensitivity of 91.5% (83.2-96.5%) and a specificity of 97.1% (93.3-99.0%). Regarding fracture classification, diagnostic performances were slightly lower, with the 10-segment classification yielding the best sensitivity of 85.7% (81.4-89.3%) and specificity of 97.4% (96.6-98.0%), and the Schatzker classification yielding the lowest sensitivity of 78.2% (67.4-86.8%) and specificity of 97.7% (94.1-99.4%). Inter-reader agreement across the whole cohort was excellent (Krippendorff's alpha 0.89-0.96) and when considering only patients with fractures, good to acceptable (0.48-0.91). Image quality was rated good (estimated marginal mean 4.3 (4.1-4.4)).

conclusionFRACTURE-MRI is feasible at 3 T enabling accurate delineation of fracture lines for precise diagnosis and classification of proximal tibial fractures. KEY POINTS: Question CT-like MRI is increasingly being evaluated for its advantages in bone imaging but is not yet established in routine practice. Findings The 3D FRACTURE (fast field echo resembling a CT using restricted echo-spacing) MRI sequence is feasible at 3 T, allowing for diagnosis and classification of proximal tibial fractures. Clinical relevance FRACTURE-MRI might be a helpful alternative to computed tomography in an acute trauma setting by reducing costs and radiation exposure in patients requiring a preoperative MRI anyway.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingTibial FracturesTomography, X-Ray ComputedAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityBoneComputed tomographyContrastMagnetic resonance imagingTibial fracture

Identifiers

PMID40126605
PMCPMC12350421

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.