Regulating AMPA Receptors with Isoxazole-4-Carboxamide Derivatives: An Electrophysiological Study.

Mohammad Qneibi, Mohammed Hawash, Sosana Bdir, Mohammad Bdair, Tala Idais, Iyas Sarhan, Joud Touqan

Abstract read

In one paragraph

Article in Journal of xenobiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad QneibiDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.ORCID 0000-0002-0702-7834

Mohammed HawashPharmaceutical Chemistry and Technology Division, Faculty of Pharmacy, An-Najah National University, P400 Nablus, Palestine.ORCID 0000-0001-5640-9700

Sosana BdirDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.ORCID 0000-0002-0540-1773

Mohammad BdairDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.ORCID 0000-0002-8968-7034

Tala IdaisDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.

Iyas SarhanDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.

Joud TouqanDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P400 Nablus, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isoxazole carboxamide derivatives are intriguing modulators of ionotropic glutamate receptors; more specifically, their prospective analgesic activities based on non-opioid pathways have sparked widespread research. α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, especially Ca

Indexed as

AMPA receptorchronic paindeactivationdesensitizationGluA2isoxazole–carboxamide

Identifiers

PMID40126258

DOI10.3390/jox15020040

PMCPMC11932207

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.