ReviewPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2025
IgE-mediated lipid transfer protein allergy in children.
Review in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- IgE-mediated lipid transfer protein allergy in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Review
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipid Transfer Protein (LTP) allergy, traditionally more prevalent in adults from Southern Europe, is increasingly recognized in pediatric populations worldwide. This review explores the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of LTP allergy in children. LTP allergy can present with severe systemic symptoms both in children and adults; in children-only studies, anaphylaxis is reported in up to half of the patients. Moreover, children often display polysensitization to multiple plant-based foods. The prevalence of LTP allergy among children remains under-researched, contributing to diagnostic and clinical practice variability. Key allergenic sources involved include peach (Pru p 3) and other Rosaceae fruits, as well as tree nuts, with cofactors such as physical activity frequently triggering or exacerbating reactions. Advancements in understanding natural tolerance and targeted therapies, along with expanding LTP immunotherapy, offer promising directions for improving the management of this challenging condition in pediatric patients.
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