Evidence map›Paper›PMID 40126018›Full record

ArticlemBio2025

Storage of the vital metal tungsten in a dominant SCFA-producing human gut microbe

Nana Shao, Dayong Zhou, Gerrit J Schut, Farris L Poole, Sydney B Coffey, Aaron P Donaghy, Saisuki Putumbaka, Michael P Thorgersen, Lirong Chen, John Rose and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. An electron-bifurcating "plug" to a protein nanowire in tungsten-dependent aldehyde detoxification.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Tungsten is utilized for lactate consumption and SCFA production by a dominant human gut microbeProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nana ShaoDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-3565-885X
Dayong ZhouDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Gerrit J SchutDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-3694-1799
Farris L PooleDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Sydney B CoffeyDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Aaron P DonaghyDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Saisuki PutumbakaDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Michael P ThorgersenDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Lirong ChenDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
John RoseDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Bi-Cheng WangDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Michael W W AdamsDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-0881-8870

Funding

W-Health: Tungsten is an Essential Metal for a Healthy Gut MicrobiomeR01GM136885 · NIGMS · UNIVERSITY OF GEORGIA · PI ADAMS, MICHAEL W. · 2020 to 2023
$2.0M
HHS | National Institutes of Health (NIH) GM 136885NIGMS NIH HHS R01 GM136885
6 · The paper itself

Abstract

Enzymes containing tungsten rather than the ubiquitous and analogous element molybdenum are prevalent in the human gut microbiome, especifically in microbes that contribute to overall gut health.

Indexed as

EubacteriumFatty Acids, VolatileGastrointestinal MicrobiomeTungstenBacterial ProteinsHumansTungsten CompoundsBacterial ProteinsFatty Acids, VolatiletungstateTungstenTungsten CompoundsEubacterium limosumhuman gut microbiomeTOBETubtungsten storageX-ray crystallography

Identifiers

PMID40126018
PMCPMC11980592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.