Evidence map›Paper›PMID 40125732›Full record

Trial reportOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury?

Ferhat Simsek, Baha Naci, Meltem Bozaci Kilicoglu, Zeynep Alkan, Osman Melih Topcuoglu, Aysegul Gormez, Gunter Hafiz, Ali Fethi Okyar

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ferhat SimsekGraduate School of Natural and Applied Sciences, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0001-9413-6395
Baha NaciDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Fenerbahce University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0003-3764-2421
Meltem Bozaci KilicogluDepartment of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0001-9952-0329
Zeynep AlkanDepartment of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0003-0454-418X
Osman Melih TopcuogluDepartment of Radiology, Faculty of Medicine, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-4008-3395
Aysegul GormezDepartment of Radiology, Faculty of Medicine, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0001-5620-2881
Gunter HafizAmerican Hospital, Istanbul, Türkiye.
Ali Fethi OkyarDepartment of Biomedical Engineering, Yeditepe University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-2561-7547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveShoulder and neck dysfunctions resulting from spinal accessory nerve injury impair quality of life. This study aims to investigate the effects of manual therapy in combination with standard physiotherapy on the mechanical properties of muscle, neck and shoulder function, pain, and quality of life in head and neck cancer patients. STUDY

designProspective, randomized, controlled, double-blind clinical trial.

settingDepartment of Otorhinolaryngology Head and Neck Surgery of a university hospital.

methodsA total of 26 participants were randomized into two groups. The control group (n = 11) received standard physiotherapy including therapeutic exercises, scar tissue massage, and education. The intervention group (n = 10) received manual therapy consisting of soft tissue, myofascial release, and mobilization techniques in combination with standard physiotherapy. Outcome measures were mechanical properties of muscle, neck and shoulder active range of motion, shoulder pain and disability, and quality of life.

resultsUpper trapezius and sternocleidomastoid muscle stiffness increased significantly in the control group (P < .01), whereas a significant reduction was observed in the intervention group compared to the control group (P = .001). A reduction in muscle thickness was observed bilaterally in both groups (P < .01). Moreover, all participants showed improvements in neck and shoulder active range of motion, shoulder pain, and quality of life (P < .01).

conclusionManual therapy in addition to standard physiotherapy was more effective in improving neck and shoulder function, quality of life, and reducing muscle stiffness compared to standard physiotherapy alone. Therefore, clinicians should consider incorporating manual therapy into their treatment protocols to optimize patient outcomes.

Indexed as

Accessory Nerve InjuriesMusculoskeletal ManipulationsNeck MusclesAdultDouble-Blind MethodFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPhysical Therapy ModalitiesProspective StudiesQuality of LifeRange of Motion, ArticularShoulder PainTreatment Outcomehead and neck cancermanual therapymechanical properties of musclemuscle stiffnessphysiotherapyshear wave elastographyspinal accessory nerve

Identifiers

PMID40125732
PMCPMC12207386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.