Evidence map›Paper›PMID 40125529›Full record

ArticleComprehensive psychoneuroendocrinology2025

Using hair biomarkers to examine social-emotional resilience in adolescence: A feasibility study.

Cynthia R Rovnaghi, Anjali Gupta, Susan Ramsundarsingh, Ronnie I Newman, Sa Shen, Jordan K H Vedelli, Elizabeth L Reichert, Kanwaljeet J S Anand

Abstract read
In one paragraph

Article in Comprehensive psychoneuroendocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Social emotional learning and autonomic regulation enhance social connectedness in female adolescents with extensive exposure to adverse childhood experiences.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cynthia R RovnaghiChild Wellness Lab, Maternal & Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, USA.
Anjali GuptaChild Wellness Lab, Maternal & Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, USA.
Susan RamsundarsinghDepartment of Social Work, University of Victoria, Victoria, British Columbia, Canada.
Ronnie I NewmanBehavioral Health Research, International Association of Human Values, Washington, D.C, USA.
Sa ShenQuantitative Statistics Unit, Stanford University School of Medicine, Stanford, CA, USA.
Jordan K H VedelliChild Wellness Lab, Maternal & Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, USA.
Elizabeth L ReichertDivision of Child Psychiatry, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Kanwaljeet J S AnandChild Wellness Lab, Maternal & Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, USA.

Funding

Do Hair Cortisol and Hair Oxytocin represent the Stressful and Supportive Experiences of Preschool Children?R01HD099296 · NICHD · STANFORD UNIVERSITY · PI KANWALJEET S ANAND · 2019 to 2026
$5.8M
NICHD NIH HHS R01 HD099296
6 · The paper itself

Abstract

Background: The SKY Schools Program combines breath-based techniques and a social-emotional learning curriculum. We examined its effects on objective physiological biomarkers, including hair cortisol (HCC, chronic stress measure) and hair oxytocin (HOC, social affiliation measure), as well as behavioral (youth risk behaviors) and mental health outcomes (anxiety, depression). Methods: The SKY Schools program was adapted for post-pandemic restrictions (i.e., staff shortages, no lessons requiring writing, limited weekly follow-ups) and implemented among 7th grade students (daily in-person 40-min sessions for three weeks during physical education classes). Longitudinal assessments were obtained at baseline (T1, February 2022, N = 21), post-intervention (T2, June 2022, N = 20), and follow-up (T3, December 2022, N = 18). Results: Most of our sample was male (67 %), Hispanic (62 %), and lived in low-income (<$100K) households (75 %). Students reported fewer poor mental health days at follow-up (Friedman test p < 0.01). Log-normal (Ln)-HCC (p < 0.01) were higher post-intervention vs. baseline (median 1.81 (IQR 1.63-2.46) vs. 1.60 (0.91-1.85)) and lower at follow-up (1.23; IQR: 0.64-1.50), with HCC in more students moving into the adaptive range (25th-75th percentile). Ln-HOC (p = 0.04) were higher post-intervention vs. baseline (1.78 (1.54-2.26) vs. 1.50 (0.81-1.70)). Conclusions: This study uniquely evaluated the impact of the SKY intervention on hair cortisol (HCC) and hair oxytocin concentrations (HOC), which are objective, physiological measures of chronic stress and social affiliation. Results suggest that SKY may improve social affiliation and possibly HPA-axis regulation.

Indexed as

BiomarkersChronic stressPovertyResilienceSudarshan kriya yoga

Identifiers

PMID40125529
PMCPMC11925592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.