Evidence map›Paper›PMID 40125527›Full record

ArticleCureus2025

Intertransverse Process Block With Catheter Placement for Postoperative Pain Management in a Patient With Alcoholic Liver Disease and Portal Hypertension: A Case Report.

Keisuke Nakazawa, Ayano Takenaka, Takahiro Suzuki

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Keisuke NakazawaDepartment of Anesthesiology, Nihon University School of Medicine, Tokyo, JPN.
Ayano TakenakaDepartment of Anesthesiology, Nihon University School of Medicine, Tokyo, JPN.
Takahiro SuzukiDepartment of Anesthesiology, Nihon University School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidural analgesia is typically avoided in patients with portal hypertension due to multiple risk factors: engorgement of epidural venous plexuses, platelet dysfunction despite normal counts, and potential postoperative coagulopathy following liver surgery. These risks persist even when preoperative coagulation parameters appear normal. While peripheral nerve blocks are increasingly utilized for minimally invasive laparoscopic procedures, intertransverse process block (ITPB) with catheter placement offers a high-quality analgesic strategy that supports early ambulation and postoperative recovery with a significantly reduced risk profile in such patients. A 76-year-old male patient with alcoholic liver cirrhosis (Child-Pugh class A) and a history of esophageal variceal bleeding underwent laparoscopic partial hepatectomy of segment 3 for suspected hepatocellular carcinoma. Despite normal coagulation parameters (prothrombin time-international normalized ratio 1.1 and activated partial thromboplastin time 33 seconds), epidural analgesia was contraindicated due to portal hypertension with multiple vascular anomalies. Bilateral ultrasound-guided ITPB was performed at the Th8-9 level with catheter placement in the intertransverse tissue complex. Analgesia was maintained with intermittent boluses of 0.25% levobupivacaine (10 mL bilaterally, twice daily) for three postoperative days, supplemented with intravenous patient-controlled analgesia (IV-PCA) fentanyl (baseline infusion 10 μg/hour, bolus dose 10 μg, lockout time 10 minutes). The patient reported minimal pain scores (numerical rating scale 0-2 at rest, 2-3 with movement), achieved early mobilization, and did not require any PCA boluses throughout recovery. Cold testing confirmed adequate sensory blockade from Th8 to Th11 on each postoperative day until catheter removal. ITPB with catheter placement provided safe and effective analgesia in a patient with portal hypertension, enabling early mobilization and rehabilitation without risking complications associated with epidural techniques. This approach represents a viable alternative to epidural analgesia in high-risk patients with compromised liver function and vascular abnormalities.

Indexed as

alcoholic liver cirrhosiscatheter techniqueepidural venous plexusesintertransverse process blockintertransverse tissue complexparavertebral by proxyportal hypertensionpostoperative analgesiaregional anesthesia

Identifiers

PMID40125527
PMCPMC11926400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.