Evidence map›Paper›PMID 40125394›Full record

ReviewFrontiers in neurology2025

Future applications of fluorescence lifetime imaging ophthalmoscopy in neuro-ophthalmology, neurology, and neurodegenerative conditions.

Daniel M Markowitz, Elizabeth Affel, György Hajnóczky, Robert C Sergott

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel M MarkowitzDrexel University College of Medicine, Philadelphia, PA, United States.
Elizabeth AffelWilliam H. Annesley, EyeBrain Center, Vicky and Jack Farber Neuroscience Institute, Thomas Jefferson University, Partnered with Wills Eye Hospital, Philadelphia, PA, United States.
György HajnóczkyMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, United States.
Robert C SergottWilliam H. Annesley, EyeBrain Center, Vicky and Jack Farber Neuroscience Institute, Thomas Jefferson University, Partnered with Wills Eye Hospital, Philadelphia, PA, United States.

Funding

Mitochondrial Calcium and Neuronal HealthR01NS132056 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI Gyorgy Hajnoczky · 2023 to 2026
$2.5M
NINDS NIH HHS R01 NS132056
6 · The paper itself

Abstract

Fluorescence lifetime imaging ophthalmoscopy (FLIO) has emerged as an innovative advancement in retinal imaging, with the potential to provide

Indexed as

Alzheimer’s diseasefluorescence lifetime imaging ophthalmoscopyneurodegenerative diseasesneuromyelitis optica spectrum disorderParkinson’s disease

Identifiers

PMID40125394
PMCPMC11927091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.