ArticleJournal of patient experience2025
Experience of the Burden of Using Multiple Medicines and the Associated Impact on Health-Related Quality of Life.
Article in Journal of patient experience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Health literacy, medication adherence, and quality-of-life scores in Jordanian adults with chronic diseases: a dual analytical study using the long-term conditions questionnaire and the EuroQol five-dimension three-level questionnaire.The Libyan journal of medicine · 2026Article
- Redeemed prescription medicines to measure quality of life of patients with long-term conditions: a national cross-sectional study.BMC medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Managing multiple medications can be challenging for many patients and negatively affect their health-related quality of life (HRQoL). This study examined the key factors that predict medication burden and HRQoL separately. The secondary aim was to investigate whether overall experience of medication burden mediates the relationship between the number of medications taken and HRQoL. A cross-sectional study was conducted with 348 participants. The average age of these participants was 31 years (SD ± 11.3 years). The average number of medications used was 3.2 (SD ± 1.6). The majority of the study participants experienced moderate (39.0%) to high (45.0%) levels of medication burden. Limited autonomy in adjusting their regimen and concerns about their medications were identified as major contributors to this burden. Hierarchical linear regression analysis indicated that overall experience of medication burden, self-rated health, and a diagnosis of diabetes mellitus significantly predicted medication burden. Similarly, self-rated health, dosing frequency, being female, and assistance with medicines were significant predictors of poor HRQoL. Mediation analysis revealed that overall experience of medication burden partially mediated the association between number of medicines used and HRQoL. These findings highlight the importance of addressing medication burden when developing interventions to avoid jeopardizing patients' HRQoL. Healthcare professionals should prioritize understanding the experiences of nonelderly patients with their medications and personalize treatment plans accordingly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.