Evidence map›Paper›PMID 40125340›Full record

ArticleJournal of the American College of Emergency Physicians open2025

Noninvasive Monitoring of Traumatic Intracranial Hematoma Progression Using the Infrascanner: Preliminary Experience.

Jan O Jansen, Elizabeth Liptrap, Jonathan Black, Shannon W Stephens, Timothy Smith, Hasan Ayaz, Meltem Izzetoglu, Lindy Reynolds, Russell L Griffin, Joshua Richman and 2 more

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jan O JansenCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Elizabeth LiptrapDepartment of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jonathan BlackCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Shannon W StephensCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Timothy SmithCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Hasan AyazSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.
Meltem IzzetogluDepartment of Electrical and Computer Engineering, Villanova University, Villanova, Pennsylvania, USA.
Lindy ReynoldsCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Russell L GriffinCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Joshua RichmanCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Alex ValadkaDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
John B HolcombCenter for Injury Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Early detection of intracranial hematoma (ICH) expansion is critical to improving outcomes in patients with traumatic brain injuries (TBIs). The Infrascanner 2000 (InfraScan Inc) is a US Food and Drug Administration-cleared device capable of detecting ICHs. We report our preliminary experience of conducting a prospective evaluation of serial infrascans to evaluate the diagnostic performance of the device for monitoring changes in ICH size. Methods: A single-center prospective observational study was conducted. We included patients with traumatic ICHs detected on admission computed tomography (CT) scanning, and conducted hourly infrascans until a second CT scan had been performed. We evaluated the practicability of enrollment, conducting hourly infrascans, and the diagnostic performance of the device. Results: We approached 134 patients, or their legally authorized representatives, and enrolled 62 (46%). Most index hematomas were small (median, 2.5 mL, IQR, 0.6-7.0 mL), and 23 experienced enlargement. Hourly infrascan assessments were performed successfully in the majority of patients (300 of 340 scans, 88%). The most common reasons for scans not being performed, or not performed on time, were technical issues with the devices (17 scans, 40%), the presence of dressings and bandages (2 scans, 5%), and patients being taken for other investigations or treatment (12 scans, 31%). Given the sample size, the small size of enrolled patients' ICHs, and the low proportion that experienced enlargement, it was not possible to demonstrate the ability of the Infrascanner to detect expansion. Conclusion: This preliminary study confirms the practicability of conducting a prospective evaluation of the Infrascanner for the purpose of serially monitoring the size of ICHs in trauma patients.

Indexed as

infrascanintracranial hematomatraumatraumatic brain injury

Identifiers

PMID40125340
PMCPMC11928848

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.