Evidence map›Paper›PMID 40125289›Full record

ArticleRespirology case reports2025

Primary Ciliary Dyskinesia Complicated by Stroke in an Elderly Male: A Case Report.

Ali Gohar, Bilal Ahmed, Asim Ali, Maryam Ilyas, Momina Masroor, Ayesha Ayman, Masab Ali, Muhammad Husnain Ahmad

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Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ali GoharDepartment of Medicine Lahore General Hospital Lahore Punjab Pakistan.
Bilal AhmedDepartment of Medicine Lahore General Hospital Lahore Punjab Pakistan.
Asim AliDepartment of Medicine Lahore General Hospital Lahore Punjab Pakistan.
Maryam IlyasDepartment of Medicine Lahore General Hospital Lahore Punjab Pakistan.
Momina MasroorDepartment of Medicine Pakistan Kidney and Liver Institute and Research Centre Lahore Punjab Pakistan.
Ayesha AymanDepartment of Medicine Pakistan Kidney and Liver Institute and Research Centre Lahore Punjab Pakistan.
Masab AliDepartment of Internal Medicine Punjab Medical College Faisalabad Punjab Pakistan.ORCID https://orcid.org/0009-0007-8599-6861
Muhammad Husnain AhmadDepartment of Medicine Satkynbay Tentishev Asian Medical Institute Kant Kyrgyzstan.ORCID https://orcid.org/0009-0006-5248-0749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kartagener syndrome (KS) is an uncommon hereditary disorder, featuring situs inversus, chronic sinusitis, and bronchiectasis. Our case report presents a 60-year-old Asian male with KS who was incidentally diagnosed with KS upon presenting with an ischemic cerebrovascular accident (CVA). The patient had a longstanding history of poorly controlled type 2 diabetes mellitus and hypertension, presenting with acute right-sided weakness and speech impairment. His history of recurrent respiratory infections and infertility, combined with family findings of dextrocardia and male infertility, suggested KS. On physical examination, the patient exhibited signs of dextrocardia. Imaging confirmed situs inversus and dextrocardia, while neurological evaluation revealed an embolic stroke in the left middle cerebral artery territory. Certain cardiovascular anomalies in KS may affect stroke risk; however, their co-occurrence in the patient appears to be coincidental, given the patient's baseline risk for stroke. A high-resolution chest CT demonstrated bronchiectasis and carotid Doppler ultrasound identified atherosclerotic plaques, likely contributing to the stroke. This case highlights the need for heightened awareness of neurological events, such as stroke, in patients with KS. Cardiovascular risk factors, compounded by the complexity of the syndrome, require prompt evaluation and multidisciplinary care to prevent severe complications.

Indexed as

cerebrovascular accidentdextrocardiaischemic strokeKartagener syndromeprimary ciliary dyskinesiasitus inversus

Identifiers

PMID40125289
PMCPMC11926249

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