Evidence map›Paper›PMID 40125260›Full record

ArticleWorld journal of pediatric surgery2025

Short-term outcomes and risk factors for mortality in neonatal cardiac surgeries with cardiopulmonary bypass: a 5-year single-center report.

Xianghong Zhang, Tingting Wen, Jiajie Fan, Yunxiang Qiu, Jiangmei Wang, Liyang Ying, Jiangen Yu, Xiangming Fan, Shengwen Song, Shanshan Shi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of pediatric surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xianghong Zhang *Department of Cardiac Intensive Care Unit, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.ORCID 0000-0001-6810-3346
Tingting Wen *Department of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID 0000-0001-5693-9760
Jiajie FanDepartment of Cardiac Intensive Care Unit, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Yunxiang QiuDepartment of Cardiac Intensive Care Unit, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Jiangmei WangDepartment of Anesthesiology, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Liyang YingDepartment of Cardiac Surgery, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Jiangen YuDepartment of Cardiac Surgery, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Xiangming FanDepartment of Cardiac Surgery, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Shengwen SongDepartment of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Shanshan ShiDepartment of Cardiac Intensive Care Unit, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Xiangming FangDepartment of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Qiang ShuDepartment of Cardiac Surgery, Zhejiang University School of Medicine Children's Hospital National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.ORCID 0000-0002-4106-6255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Open-heart surgeries carry significantly greater risks in neonates than in older children. The current study aimed to analyze the short-term outcomes and risk factors for mortality in neonates undergoing cardiac surgeries. Methods: This retrospective analysis included neonates who underwent cardiac surgeries with cardiopulmonary bypass (CPB) at our center between 2019 and 2023. Perioperative and operative factors were collected, and in-hospital outcomes and risk factors for mortality were identified. Results: We analyzed the medical records of 190 neonates, including 111 males and 79 females. The median age at the time of surgery was 15 days, with a median weight of 3.2 kg. The overall mortality rate was 11.6%. Major postoperative complications included infection (48.9%), low cardiac output (48.4%), hepatic insufficiency (24.9%), acute kidney injury (22.1%), unplanned reintervention (13.1%), intracranial hemorrhage (3.7%), and cerebral infarction (0.5%). Multivariable analysis identified prolonged CPB time (odds ratio (OR)=1.018, Conclusions: Despite advancements in recent decades, continued vigilance is required to further reduce mortality rates among neonates undergoing cardiac surgeries.

Indexed as

CardiologyMortalityNeonatology

Identifiers

PMID40125260
PMCPMC11927473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.