Evidence map›Paper›PMID 40125257›Full record

SynthesisWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2024

Efficacy of different preoperative antiseptics in preventing a risk of surgical site infections: a systematic review and meta‑analysis of randomized controlled trials.

Lutao Yang, Shunxin Liao, Qing Cao, Sanjay Rastogi

Abstract readSystematic Review
In one paragraph

Synthesis in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lutao YangDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No.1 People's Hospital, Jiujiang, China.
Shunxin LiaoDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No.1 People's Hospital, Jiujiang, China.
Qing CaoDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No.1 People's Hospital, Jiujiang, China.
Sanjay RastogiBoston University Medical Campus, Boston, Massachusetts, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurgical site infection (SSI) is a predominant postoperative complication that markedly increases health care expenses. Published systematic reviews, meta‑analyses and international guidelines vary in their recommendations for the most effective preoperative skin antiseptic solutions and their concentrations.

aimThe aim of this study was to assess the efficacy of different preoperative antiseptics for prevent‑ ing the risk of SSIs. MATERIALS AND

methodsA complete search was conducted using PubMed, EMBASE, Scopus, and Cochrane Library databases to collect peer‑reviewed articles.

resultsThis meta‑analysis included 10 587 surgical patients from 18 randomized clinical trials to determine the effectiveness of chlorhexidine in alcohol (CHA; 0.5%, 2%-2.5%, and 4%) with aqueous or alcoholic iodine in preventing postoperative SSIs. This meta‑analysis found that 2%-2.5% CHA is the most effective preoperative antiseptic for preventing SSIs, with significant reduction in their incidence and significant antimicrobial activity.

conclusionsThe findings of this meta‑analysis indicate that for patients undergoing any type of surgery, the use of 2%-2.5% CHA for skin preparation is the most effective method for preventing SSIs.

Indexed as

chlorhexidine alcoholpostoperative wound infectionpreoperative skin antisepticssurgical site infectionsvarious surgeries

Identifiers

PMID40125257
PMCPMC11927555

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.