ArticleCureus2025
Assessment and Comparison of Natural Dyes Like Lawsonia inermis, Zingiber officinale, Curcuma longa, Beta vulgaris, Kumkum, and Hibiscus rosa-sinensis With Eosin as a Cytoplasmic Stain in Oral Histopathologies.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background Hematoxylin and eosin (H&E) staining is a commonly used technique in histology and histopathology. However, the synthetic dye eosin poses risks to both human and animal health. The growing ecological concern has led to efforts to find natural, less toxic, biodegradable, and cost-effective alternatives to eosin. Aim This study aimed to compare and evaluate the staining characteristics of natural dyes as cytoplasmic stain to eosin as a standard in oral histopathologies. Materials and methods A total of 140 histological sections from four tissue types (normal mucosa, oral squamous cell carcinoma, ameloblastoma, and odontogenic cysts) were stained with natural dyes. The groups were divided based on the type of stain: Group A (
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