Evidence map›Paper›PMID 40125161›Full record

ArticleCureus2025

Euglycemic Diabetic Ketoacidosis (DKA) With Sodium-Glucose Transport Protein 2 (SGLT-2) Inhibitors.

Ahmed Malik, Eiman Ahmed, Sara Hamid, Mohammed Ahmed, Hossam Abdalla

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed MalikAcute Internal Medicine, University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Eiman AhmedInternal Medicine, University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Sara HamidAcute Internal Medicine, University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Mohammed AhmedAcute Internal Medicine, University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Hossam AbdallaNeurology, University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, Stoke-on-Trent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case highlights a rare yet severe presentation of euglycemic diabetic ketoacidosis (DKA) in a male in his mid-eighties with type 2 diabetes mellitus managed on SGLT-2 inhibitors. Despite nearly normal blood glucose levels, he developed profound metabolic acidosis and elevated ketones, necessitating emergency intervention. Initial treatment with intravenous fluids and insulin led to temporary stabilization. Still, progressive metabolic derangement and multi-organ dysfunction resulted in a transition to palliative care, ultimately leading to his demise. This case underscores the need for heightened clinical awareness, early diagnosis, and cautious use of SGLT-2 inhibitors, particularly in elderly patients with multiple comorbidities.

Indexed as

critical carediabetes complicationseuglycemic dkametabolic acidosissglt-2 inhibitors

Identifiers

PMID40125161
PMCPMC11927945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.