Evidence map›Paper›PMID 40125144›Full record

ArticleCureus2025

Papillary Carcinoma Arising From Thyroglossal Duct Cysts: A Case Series and Management Strategies.

Adhithya N Balaji, Balaji Balasubramanian, Amritaa Thalla, Yogesh Gohil, Panna Shetty

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adhithya N BalajiInternal Medicine, Università Cattolica Del Sacro Cuore, Rome, ITA.
Balaji BalasubramanianSurgery and Oncology, New Medical Centre (NMC) Specialty Hospital, Abu Dhabi, ARE.
Amritaa ThallaInternal Medicine, Maheshwara Medial College and Hospital, Isnapur, IND.
Yogesh GohilRadiology, New Medical Centre (NMC) Specialty Hospital, Abu Dhabi, ARE.
Panna ShettyPathology, New Medical Centre (NMC) Royal Hospital, Khalifa City, Abu Dhabi, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary carcinoma arising from thyroglossal duct cysts is a rare entity, most often detected after surgery. Despite its excellent prognosis, management remains controversial. In this report, we present three cases of papillary carcinoma in thyroglossal duct cysts. In two of the three cases, malignancy was identified in both the thyroglossal duct cyst and the thyroid gland at the time of presentation. In contrast, the third case was diagnosed with malignancy only after surgery for the thyroglossal duct cyst, ultimately necessitating a total thyroidectomy. A high degree of suspicion and clinical awareness are required during evaluation of this rare situation which is otherwise usually a benign lesion. For low-risk patients with papillary carcinoma involving only the thyroglossal duct cyst, the Sistrunk procedure (resection of the thyroglossal duct cyst) is adequate. For high-risk cases of papillary carcinoma of the thyroglossal duct cyst with an associated malignancy of the thyroid gland, total thyroidectomy, central compartment nodal dissection, and radioactive iodine ablation are needed.

Indexed as

papillary carcinomasistrunk procedurethyroglossal duct cystthyroidectomythyroid neoplasm

Identifiers

PMID40125144
PMCPMC11929959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.