Evidence map›Paper›PMID 40125136›Full record

ArticleCureus2025

Vaginal Metastasis of Colorectal Cancer Treated With Image-Guided Intracavitary-Interstitial Brachytherapy: A Case Report.

Soichiro Sakamoto, Ken Ando, Takuya Kumazawa, Takahiro Oike, Tatsuya Ohno

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Soichiro SakamotoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, JPN.
Ken AndoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, JPN.
Takuya KumazawaDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, JPN.
Takahiro OikeDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, JPN.
Tatsuya OhnoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastasis of a colorectal primary tumor to the vagina is an uncommon condition, and its treatment strategies have not been well established. Computed tomography (CT)-guided intracavitary-interstitial (IC-IS) brachytherapy uses a few interstitial needles, in addition to conventional intracavitary applicators (such as the Fletcher-Suit applicator or vaginal cylinder), and achieves conformal dose distribution to bulky and/or irregularly shaped tumors. Here, we report a first case of an oligometastatic vaginal tumor from the colorectum that was treated successfully with radiotherapy using CT-based IC-IS brachytherapy. External beam radiotherapy (EBRT), followed by four sessions of IC-IS brachytherapy, resulted in a satisfactory dose prescription to the target while sparing normal organs adjacent to the tumor. This led to radiological complete remission of the tumor over at least six months, with no severe adverse effects. This case indicates that radiotherapy using CT-based IC-IS brachytherapy may be a viable treatment option for metastatic vaginal tumors.

Indexed as

colorectal cancerimage-guided brachytherapyintracavitary-interstitial brachytherapyoligometastasisradiation therapyvaginal metastasis

Identifiers

PMID40125136
PMCPMC11925722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.