ArticleCureus2025
Impact of Low Hepatitis Delta Virus Screening Rates on the Accurate Estimation of Seroprevalence in Florida: A Retrospective Observational Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Providers' Perspectives of Hepatitis Delta Virus Screening and Recommendations for Improvement: A Qualitative Investigation.Gastro hep advances · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundHepatitis delta virus (HDV) is a hepatotropic virus that can accelerate the progression of liver disease to cirrhosis and is associated with an increased risk of liver-related mortality and liver cancer. As a defective single-stranded RNA virus, it can only occur with acute hepatitis B or in patients with chronic hepatitis B virus (HBV) infections. In light of these risks, current screening guidelines recommend universal screening in all hepatitis B surface antigen (HBsAg)-positive individuals and those at risk for HDV. Unfortunately, HDV seroprevalence data remains limited due to low rates of HDV screening in the US and worldwide.
aimThe aim of this study is to determine HDV regional screening rates, prevalence, and associated factors using OneFlorida research data.
methodsAdult patients aged 18-99 with a previous HBV diagnosis were identified using OneFlorida+ Clinical Research Network data. Using International Classification of Diseases codes, HBV-positive patients were categorized as definite, probable, or possible. This data was then analyzed using a two-sample t-test to determine possible associations with race, gender, or age.
resultsWe found that among patients who were tested, HDV seroprevalence was 4.7%. Of the total of 8,744 individuals included in the study, only 225 (2.6%) underwent HDV antibody testing. Although there was no significant difference in age or race, males were more likely to undergo HDV testing.
conclusionDespite a low screening rate, HDV seroprevalence in Florida was approximate to previous estimations of HDV positivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.