ArticleRisk management and healthcare policy2025
Analysis of Risk Factors for Poor Prognosis Following Small Artery Occlusion or Lacunar Stroke: A Retrospective Cohort Study.
Article in Risk management and healthcare policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the risk factors and predictive value for poor prognosis following small artery occlusion stroke (SAO) or lacunar stroke. Methods: A retrospective cohort of 100 SAO patients who received their first intravenous thrombolysis (IVT) treatment with alteplase between March 2019 and March 2021 was collected. Based on the modified Rankin Scale (mRS) score of <3 at 90 days post-admission, patients were divided into a good prognosis group (61 cases) and a poor prognosis group (39 cases) for comparative analysis. Results: In our retrospective cohort study of 100 SAO patients treated with IVT from March 2019 to March 2021, we found no significant differences in gender, age or BMI between the 61 patients with good prognosis and the 39 with poor prognosis, although smoking habits varied. Statistically differences were observed between the two groups in terms of time from onset to hospital admission for thrombolysis (48.59±20.14 vs 40.03±23.73 min, Conclusion: An extended duration from onset to hospital admission for thrombolysis and smoking are identified as significant risk factors for poor prognosis following thrombolysis in SAO patients, both of which have substantial predictive value.
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