ReviewIndian dermatology online journal
Role of Polyethylene Glycol in Dermatology.
Review in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Photophysical Investigation of Coumarin Solubilization in Polyethylene Glycol Mediated by a 1,2,4-Triazolium Protic Ionic Liquid.ACS omega · 2026Article
- Engineered zero-order drug release from degradable PEG hydrogels - A rapamycin case study.Journal of biomaterials applications · 2026Article
- Minimal Systemic Exposure with Maximal Delgocitinib Cream Use in Patients with Severe Chronic Hand Eczema in the DELTA 2 Randomized, Vehicle-Controlled, Double-Blind, Phase 3 Trial.Dermatology and therapy · 2026Article
- Anti-PEG Immunogenicity of mRNA-LNP Vaccines in Humans: Evidence for Population-Level Changes in the Anti-PEG Antibody Repertoire.Pharmaceutics · 2026Article
- Development and Study of Hydrophilic Ointment Compositions with a Dextrin/Polyvinyl Alcohol/Iodine Complex (D/PVA/I).Pharmaceuticals (Basel, Switzerland) · 2026Article
- Recent advances in polymer-based drug delivery systems for atopic dermatitis: enhancing therapeutic efficacy and outcomes.Materials today. Bio · 2025Review
- [Drug Excipients. Necessary, but not Harmless].Farmaceuticos comunitarios · 2025Review
- A Comprehensive Review of Azelaic Acid Pharmacological Properties, Clinical Applications, and Innovative Topical Formulations.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Polyethylene glycol (PEG) is commonly used in dermatology due to its excellent solubility, nontoxic nature, and compatibility with various therapeutic agents. Its applications extend from moisturizing creams to chemical peels, improving skin hydration and facilitating drug delivery. Despite its broad utility, PEG is associated with hypersensitivity reactions, including rare cases of anaphylaxis, that necessitates a thorough assessment of its safety profile. This review evaluates PEG's therapeutic roles, safety, and dermatological applications, focusing on its pharmacokinetics, chemical properties, and potential adverse effects. Methods: A comprehensive literature search was conducted in PubMed, SciVerse, and EMBASE databases to identify studies on PEG's dermatological uses, including its role in treating psoriasis, acne, ichthyosis, fungal infections, wound healing, and cosmeceuticals. Studies addressing PEG's allergenic potential were also reviewed, focusing on cutaneous reactions and rare anaphylactic events. Articles in English, published until June 2024, were included in this narrative review. Results: PEG's emollient and humectant properties make it valuable in treating psoriasis, where it enhances corticosteroid delivery and reduces erythema and scaling. In acne, PEG-based salicylic acid peels offer controlled exfoliation with minimal irritation. PEG's hydrating properties also benefit ichthyosis and wound healing by maintaining moisture and delivering antibacterial agents. In cosmetics, PEG functions as an emulsifier, surfactant, and conditioner. However, hypersensitivity risks, including urticaria and anaphylaxis, require cautious use, especially for allergy-prone individuals. Conclusion: PEG's properties make it a useful dermatological component, though awareness of hypersensitivity risks is essential for safe clinical use. Further studies are needed to understand PEG-induced hypersensitivity and to guide safety protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.