Evidence map›Paper›PMID 40124923›Full record

ArticleHealth science reports2025

Building a Healthier Future: A Narrative Review on Early Infant Diagnosis's Role in HIV Prevention.

Emmanuel Ifeanyi Obeagu, Getrude Uzoma Obeagu

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emmanuel Ifeanyi ObeaguDepartment of Biomedical and Laboratory Science Africa University Mutare Zimbabwe.ORCID 0000-0002-4538-0161
Getrude Uzoma ObeaguSchool of Nursing Science Kampala International University Kampala Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Early infant diagnosis (EID) is a critical intervention in the global fight against pediatric HIV, providing early identification and treatment for HIV-exposed infants. This narrative review examines the role of EID in reducing vertical transmission, improving health outcomes, and mitigating stigma in communities. The review also explores innovations, challenges, and strategies for optimizing EID programs. Methods: A comprehensive literature search was conducted across databases such as PubMed, Scopus, and WHO reports to identify relevant studies, guidelines, and program evaluations. Key focus areas included diagnostic techniques, implementation strategies, and community impacts of EID programs, with an emphasis on their integration into broader HIV care frameworks. Results: EID enables the early detection of HIV in infants, allowing timely initiation of antiretroviral therapy (ART), which reduces morbidity and mortality. It also indirectly prevents postnatal transmission during breastfeeding by lowering viral loads in treated infants. Innovations such as point-of-care testing and digital health tools have improved access and efficiency, particularly in resource-limited settings. EID programs have demonstrated a positive societal impact by raising awareness, reducing stigma, and fostering trust in healthcare systems. However, significant challenges persist, including logistical barriers, infrastructure limitations, and socioeconomic constraints that hinder program effectiveness. Conclusion: EID is essential for addressing pediatric HIV, contributing to the elimination of vertical transmission and improving outcomes for HIV-exposed infants. To enhance its impact, stakeholders must prioritize expanding access to diagnostic tools, strengthening healthcare infrastructure, and engaging communities through education and advocacy. EID programs not only save lives but also foster societal shifts towards inclusivity and acceptance, paving the way for a healthier, HIV-free future.

Indexed as

antiretroviral therapyearly infant diagnosis (EID)HIV preventionHIV screeninginfant healthpediatric HIVpublic health

Identifiers

PMID40124923
PMCPMC11925723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.