ArticleRSC advances2025
Copper-promoted oxidative mono- and di-bromination of 8-aminoquinoline amides with HBr and DMSO.
Changdong Shao, Jingyi Liu, Yanan Shen, Li Li, Chen Ma, Zhengsong Hu, Yuhe Kan, Ping Chen, Tingting Zhang
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9 authors.
Changdong ShaoJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.ORCID https://orcid.org/0000-0002-8691-5177 Jingyi LiuJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
Yanan ShenJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
Li LiJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
Chen MaJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
Zhengsong HuJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
Yuhe KanJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.ORCID https://orcid.org/0000-0002-2082-6796 Ping ChenJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.ORCID https://orcid.org/0000-0002-0216-475X Tingting ZhangJiangsu Provincial Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry and Chemical Engineering, Huaiyin Normal University Huai'an, 223300 Jiangsu China shaochangdong@hytc.edu.cn.
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No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
An efficient and convenient method for oxidative mono- and di-bromination of 8-aminoquinoline amides is presented, utilizing hydrogen bromide (HBr) as the brominating reagent and dimethyl sulfoxide (DMSO) as a mild oxidant. Copper salts act as Lewis acid catalysts, facilitating the bromination process. The formation of C5-monobrominated products is promoted by copper sulfate (CuSO
Identifiers
PMID40124911
PMCPMC11926796
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