Evidence map›Paper›PMID 40124689›Full record

ArticleOxford medical case reports2025

Double the trouble: pulmonary enteric adenocarcinoma with synchronous contralateral pulmonary adenocarcinoma.

Kyle Yuan, Melissa M Van Dellen, Joshua L Fenderson

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyle YuanInternal Medicine Residency Program, San Antonio Uniformed Services Health Education Consortium, 3551 Roger Brooke Dr, JBSA Fort Sam Houston, TX 78234, United States.ORCID https://orcid.org/0000-0002-3248-1799
Melissa M Van DellenDepartment of Pathology, Brooke Army Medical Center, 3551 Roger Brooke Dr, JBSA Fort Sam Houston, TX 78234, United States.
Joshua L FendersonDepartment of Hematology/Oncology, Brooke Army Medical Center, 3551 Roger Brooke Dr, JBSA Fort Sam Houston, TX 78234, United States.ORCID https://orcid.org/0000-0003-1887-8869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of non-small cell lung cancer with morphological and immunohistochemical features that are nearly indistinguishable from those of metastatic colorectal carcinoma. Owing to these overlapping features, diagnosis and treatment of PEAC can present a clinical challenge. We report the case of a 78-year-old man with synchronously diagnosed locally advanced pulmonary adenocarcinoma of the left lower lobe and localized right lower lobe PEAC. These malignancies exhibited distinct tumor molecular profiles and differed in their kinetic response to chemoimmunotherapy. We describe plausible mechanisms by which two distinct pulmonary malignancies are present in the contralateral lobes. To the best of our knowledge, this is the first reported case of synchronous invasive pulmonary adenocarcinoma and PEAC.

Indexed as

adenocarcinomacolorectalcontralateralenteric featurespulmonary enteric adenocarcinomasynchronous

Identifiers

PMID40124689
PMCPMC11924365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.