ReviewDiscoveries (Craiova, Romania)
Public Health Threats Posed by Biofilms and Innovative Strategies for their Control.
Review in Discoveries (Craiova, Romania). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Current Insights into Antibiotic Resistance in UropathogenicAntibiotics (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms are communities of microorganisms that adhere to surfaces within a self-produced protective matrix. The structural complexity of biofilms and their inherent resistance to conventional antimicrobial treatments make them a significant public health challenge. These microbial communities, embedded within a self-produced extracellular matrix, are associated with numerous persistent infections, especially those occurring in healthcare settings where they colonize medical devices and chronic wounds. The effects of biofilms go beyond healthcare environments and persist in water treatment facilities, food processing plants, and nature, in which biofilms aid in pollution and transmission of disease. This review article discusses multifaceted public health complications related to biofilms and the search for existing control strategies, the process of biofilm formation, mechanisms of persistence, and limitations of traditional antimicrobial approaches. Additionally, this article explores new innovative solutions, such as bacteriophage therapy, matrix-degrading enzymes, and quorum sensing inhibitors. The potential of a combination of antimicrobial agents with biofilm-disrupting compounds for the improvement of efficacy is also paid special attention. This review seeks to contribute to these ongoing efforts by presenting an overview of biofilm biology and assessing the efficacy of a variety of possible control strategies. Subsequently, the insights derived from this study may be used to inform future research directions and aid in the development of more effective interventions for biofilm-associated infections and contamination in various settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.