Evidence map›Paper›PMID 40124576›Full record

ArticleClinical, cosmetic and investigational dentistry2025

Comparative Mucosal Wetting Capacity of Novel and Commercial Saliva Substitute Formulations: An in vitro Study.

Wipaporn Kajornwongwattana, Nutchaporn Sanguansin, Thanapat Songsak, Suchada Vuddhakanok, Supanee Thanakun

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wipaporn Kajornwongwattana *Department of Pharmacology, Faculty of Medicine, Kasetsart University, Bangkok, 10900, Thailand.ORCID 0009-0009-0628-1839
Nutchaporn Sanguansin *Division of Oral Diagnostic Science, College of Dental Medicine, Rangsit University, Pathumthani, 12000, Thailand.
Thanapat SongsakDepartment of Pharmacognosy, College of Pharmacy, Rangsit University, Pathumthani, 12000, Thailand.ORCID 0000-0003-4218-7988
Suchada VuddhakanokCollege of Dental Medicine, Rangsit University, Pathumthani, 12000, Thailand.
Supanee ThanakunDivision of Oral Diagnostic Science, College of Dental Medicine, Rangsit University, Pathumthani, 12000, Thailand.ORCID 0000-0002-2570-0658

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study evaluated the effectiveness of novel, inexpensive saliva substitute formulas (Rangsit University (RSU) preparation) in maintaining mucosal wetness compared with commercial products. Materials and Methods: In vitro experiments were conducted using swine tongues to assess the wetness of various RSU saliva substitute solutions and gels, with four flavors each (sweet mint, sweet vanilla, sweet-sour mint, and sweet-sour lemon), compared with water, hospital-based mouth rinse from a government dental school, and commercial products (Biotene Results: All saliva substitutes consistently maintained a higher relative wetness than water, particularly beyond 60 minutes ( Conclusion: Our novel saliva substitute formulas show similar effectiveness to commercial products in maintaining mucosal wetness. These inexpensive products could be a viable alternative for patients with dry mouth who cannot afford commercial formulations.

Indexed as

artificial salivamouth drynessmouthwashxerostomia

Identifiers

PMID40124576
PMCPMC11930238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.