Evidence map›Paper›PMID 40124485›Full record

ArticleiScience2025

Correlative multiscale 3D imaging of mouse primary and metastatic tumors by sequential light sheet and confocal fluorescence microscopy.

Jingtian Zheng, Yi-Chien Wu, Xiaoying Cai, Philana Phan, Meghna Gill, Ekrem Emrah Er, Zongmin Zhao, Zaijie J Wang, Steve Seung-Young Lee

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jingtian ZhengDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Yi-Chien WuDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Xiaoying CaiDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Philana PhanDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Meghna GillDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Ekrem Emrah ErDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA.
Zongmin ZhaoDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Zaijie J WangDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.
Steve Seung-Young LeeDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA.

Funding

Molecular mechanism and targeting of chronic pain in sickle cell diseaseR35HL140031 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WANG, ZAIJIE JIM · 2018 to 2024
$4.6M
Integrated three-dimensional (3D) microscopy for a spatial pharmacology atlas of macromolecular drugs in the tissue microenvironmentR35GM142743 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEE, STEVE SEUNG-YOUNG · 2021 to 2025
$2.3M
Molecular Mechanism and Targeting of Chronic Pain in Sickle Cell DiseaseR35HL177406 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Zaijie Jim Wang · 2025 to 2026
$2.2M
MECHANOSURVEILLANCE IN BREAST CANCER METASTASISR37CA269370 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Ekrem Emrah Er · 2022 to 2026
$1.8M
Nanoparticle-coated macrophages for targeted disruption of YAP/TEAD interactions in breast cancer brain metastasisR21CA291723 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ER, EKREM EMRAH, ZHAO, ZONGMIN · 2024 to 2024
$411k
NCI NIH HHS R21 CA291723NCI NIH HHS R37 CA269370NHLBI NIH HHS R35 HL140031NHLBI NIH HHS R35 HL177406NIGMS NIH HHS R35 GM142743
6 · The paper itself

Abstract

Three-dimensional (3D) optical microscopy permits

Indexed as

CancerOptical imaging

Identifiers

PMID40124485
PMCPMC11928867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.