Evidence map›Paper›PMID 40124484›Full record

ArticleiScience2025

Swi4-dependent SWI4 transcription couples cell size to cell cycle commitment.

Pooja Goswami, Abhishek Ghimire, Carleton Coffin, Jing Cheng, Jasmin Coulombe-Huntington, Ghada Ghazal, Yogitha Thattikota, María Florencia Guerra, Mike Tyers, Sylvain Tollis and 1 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pooja GoswamiDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Abhishek GhimireDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Carleton CoffinDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Jing ChengProgram in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Jasmin Coulombe-HuntingtonInstitute of Research in Immunology and Cancer, University of Montreal, Montreal, QC H3T1J4, Canada.
Ghada GhazalInstitute of Research in Immunology and Cancer, University of Montreal, Montreal, QC H3T1J4, Canada.
Yogitha ThattikotaProgram in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
María Florencia GuerraDepartment of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology, University of Eastern Finland, 70210 Kuopio, Finland.
Mike TyersProgram in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Sylvain TollisInstitute of Research in Immunology and Cancer, University of Montreal, Montreal, QC H3T1J4, Canada.
Catherine A RoyerDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth-dependent accumulation of the G1/S transcription factor SBF, composed of Swi4 and Swi6, occurs in G1 phase in budding yeast and is limiting for commitment to division, termed Start. Here, we investigate the mechanisms for the size dependence of Swi4 accumulation using different genetic contexts and quantitative scanning number and brightness microscopy. Mutation of SBF binding sites in the

Indexed as

Cell biologyMolecular biology

Identifiers

PMID40124484
PMCPMC11930368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.