ArticleiScience2025
Identifying and analyzing the microplastics in human aqueous humor by pyrolysis-gas chromatography/mass spectrometry.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Micro- and nanoplastics in human biological materials: a systematic review of detection methods and methodological challenges.Archives of toxicology · 2026Pooled it
- Review
- The Human Plastiphere: A Bioparticulate System Challenging Microplastic Risk Assessment and Governance.Environmental science & technology · 2025Review
- Oculomics meets exposomics: a roadmap for applying multi-modal ocular biomarkers in precision environmental health research.Exposome · 2025Review
- Microplastics and nanoplastics in the ocular environment: Pathways, toxic effects, and future challenges.Current research in toxicology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics (MPs), an emerging global pollutant, pose potential risks to human health and have garnered increasing attention. Previous research has identified MPs in various human tissues and organs, but not in the aqueous humor of the eyes. This study used pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) to explore MPs in aqueous humor. Five types of MPs-polyethylene (PE), polyvinyl chloride (PVC), polypropylene (PP), polyamide 66 (PA66), and polystyrene (PS)-were found, with PE and PVC being most common. PP was more prevalent in children, while PA66 was more common in adults. MPs abundance generally followed the trend: adults > children > elders among age groups, and females > males between gender groups. Notably, this study is the first to confirm MPs in human aqueous humor, providing a foundation for future research on their impact on intraocular health and enhancing our understanding of the MPs' body distribution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.