Evidence map›Paper›PMID 40124442›Full record

ArticleOman journal of ophthalmology

Clinical outcome of eplerenone in the management of acute central serous chorioretinopathy.

Pramod Kumar Sharma, Bhagyashree Padhan, Ipsita Khuntia, Madhumita Naik, Biswambara Satpathy

Abstract read
In one paragraph

Article in Oman journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pramod Kumar SharmaDepartment of Ophthalmology, VIMSAR, Burla, Sambalpur, Odisha, India.
Bhagyashree PadhanDepartment of Ophthalmology, VIMSAR, Burla, Sambalpur, Odisha, India.
Ipsita KhuntiaDepartment of Ophthalmology, FM Medical College, Balasore, Odisha, India.
Madhumita NaikDepartment of Ophthalmology, VIMSAR, Burla, Sambalpur, Odisha, India.
Biswambara SatpathyDepartment of Ophthalmology, VIMSAR, Burla, Sambalpur, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the clinical outcomes of eplerenone in the management of acute central serous chorioretinopathy (CSCR). MATERIALS AND

methodsThis case-control study involved 52 eyes of 52 cases of acute CSCR divided between treatment (26) and control (26) groups. Cases in the treatment group were managed by tablet eplerenone 50 mg/d. During the scheduled visits, serum electrolytes and an ophthalmic evaluation, including optical coherence tomography, were conducted. The control group was subject to observation and a similar follow-up. The Statistical Programme for Social Sciences, version 23 was used for statistical tests.

resultsThe mean age in the treatment and control group was 39.15 ± 12.1 years and 36.1 ± 8.09 years, respectively. In the treatment group, 46.15% of right eyes and 53.8% of left eyes, and in the control group, 61.5% of right eyes and 38.5% of left eyes were evaluated. Visual acuity improved to 6/6 in 96.2% of treated cases and 19.2% of controls in the 2

conclusionAcute CSCR cases managed with oral eplerenone can attain faster resolution with significant functional improvement. Eplerenone may serve as a first-line therapeutic option for acute CSCR with a better safety profile.

Indexed as

Acute central serous chorioretinopathycentral macular thicknessmineralocorticoid antagonistoptical coherence tomographysubretinal fluid

Identifiers

PMID40124442
PMCPMC11925376

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.