Evidence map›Paper›PMID 40124367›Full record

ArticleFrontiers in immunology2025

Heme oxygenase-1 modulates CD62E-dependent endothelial cell-monocyte interactions and mitigates HLA-I-induced transplant vasculopathy in mice.

Laura Schuster, Marcin Zaradzki, Henrike Janssen, Nadia Gallenstein, Melanie Etheredge, Ilse Hofmann, Markus A Weigand, Stephan Immenschuh, Jan Larmann

Abstract read
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In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura SchusterDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Marcin ZaradzkiDepartment of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Henrike JanssenDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Nadia GallensteinDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Melanie EtheredgeDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Ilse HofmannDivision of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Markus A WeigandDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Stephan ImmenschuhDepartment of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.
Jan LarmannDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main risk factor for developing transplant vasculopathy (TV) after solid organ transplantation is

Indexed as

Endothelial CellsHeme Oxygenase-1MonocytesVascular DiseasesAnimalsCell AdhesionCell CommunicationDisease Models, AnimalHumansMaleMembrane ProteinsMiceMice, Inbred C57BLHeme Oxygenase-1Hmox1 protein, mouseMembrane Proteinsaccommodationadhesionanti-HLA-1 antibodieschronic rejectionendothelial cellsheme oxygenase-1monocyte transmigrationtransplantation

Identifiers

PMID40124367
PMCPMC11925954

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.