ReviewMaterials today. Bio2025
Versatile application of magnesium-related bone implants in the treatment of bone defects.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Multi-biomimetic poly(amino acid)-based Janus membrane integrating barrier and osteoinductive functions for cranial bone regeneration.Materials today. Bio · 2026Article
- Optimized Ag enhances antibacterial activity and corrosion resistance of extruded Mg-2Zn-0.2Ca alloy.iScience · 2026Article
- Long-term evaluation of plasma electrolytic oxidation (PEO) surface-modified WE43MEO magnesium alloy screws and plates reveals safe and controlled degradation in a 18-month minipig model.Journal of orthopaedic translation · 2026Article
- Metallic topological structures in bone repair implants: Design, properties, and biological interactions.Journal of orthopaedic translation · 2026Review
- Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering.Regenerative biomaterials · 2026Review
- Bifunctional 3D-printed PEEK scaffolds incorporating hydrogel-encapsulated magnesium-quinone nanosheets for antibacterial activity and mandibular bone regeneration.Materials today. Bio · 2025Article
- Micro-CT and Histomorphometric Analysis of Degradability and New Bone Formation of Anodized Mg-Ca System.Biomimetics (Basel, Switzerland) · 2025Article
- The Characterization of Physicochemical, Nutritional, and Flavor Properties of Bovine Hide Gelatin Prepared from Different Raw Materials.Foods (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnesium-related bone implants have garnered significant attention in the treatment of bone defects. The applications of magnesium in promoting bone repair mainly include degradable magnesium-based scaffolds owing to its special physical properties and composite materials modified by magnesium ions because of its biological activity. Although numerous studies have confirmed the unique application advantages and efficacy of magnesium in promoting bone repair, some obvious shortcomings persist, including the rapid degradation of magnesium-based scaffolds. In this review, the deficiencies of magnesium and its alloys in the construction of orthopedic implants and their key influencing factors were summarized; furthermore, some advanced improvement schemes were summarized and analyzed. Additionally, the application strategies of magnesium-modified bone implants are summarized and discussed. Lastly, this review incorporates the latest research and discoveries on magnesium in orthopedic science, comprehensively exploring the mechanism of magnesium's role in the complex microenvironment of bone defects from multiple dimensions. This paper provides a comprehensive summary and analysis of cutting-edge concepts in the design and development of magnesium-based bone implants, considering various perspectives such as the physical properties and biological functions of magnesium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.