Evidence map›Paper›PMID 40124308›Full record

ArticleOphthalmology science

Submacular Choroidal Arteries: A Laser Doppler Holography and OCT Study.

Michel Paques, Zosia Bratasz, Leo Puyo, Céline Chaumette, Daniela Castro Farias, Michael Atlan, Sarah Mrejen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michel PaquesParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.
Zosia BrataszInstitut Langevin, Centre National de la Recherche Scientifique (CNRS), Paris Sciences and Lettres University, École Supérieure de Physique et de Chimie Industrielles, Paris, France.
Leo PuyoParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.
Céline ChaumetteParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.
Daniela Castro FariasParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.
Michael AtlanParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.
Sarah MrejenParis Eye Imaging Group, Clinical Investigation Center 1423, Quinze-Vingts Hospital, Institut National de la Santé et de la Recherche Medicale-DIrection de l'Hospitalisation et de l'Offre de Soins, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To document the aspect, topography and morphometry of normal human choroidal arteries in the posterior pole by laser Doppler holography (LDH) and OCT. Design: Cross-sectional study. Subjects: Fifty-four eyes of 27 healthy subjects. Methods: A prototypic LDH system captured the laser Doppler shift of the choroidal circulation within the central 20°. Doppler shifts were filtered to extract high velocity vessels. Images of choroidal arteries identified by LDH were subsequently registered with Main Outcome Measures: Spatial disposition, distribution, and diameters of choroidal arteries. Results: Choroidal arteries were identified by LDH and OCT from their emergence from short posterior ciliary arteries (sPCAs), and could be traced to second and third divisions. In the 8 eyes that underwent LDH, 7 of 8 (88%) showed a horizontal first-order artery within 0.5 disc diameter from the fovea. OCT B-scans showed that first-order arteries were located along the sclera-choroid interface; around arteries, the choroidal tissue formed a pyramid-shaped avascular structure with a posterior base contiguous and isoreflective to the sclera. In a cohort of 49 eyes, the diameter of horizontal submacular arteries (average [± standard deviation] 136.3 μm [±47]; range, 70-209 μm) was weakly correlated to central choroidal thickness ( Conclusions: First-order choroidal arteries emerging from sPCAs are located along the sclerochoroidal interface and are surrounded by a pyramid-shaped avascular space, which contributes to differentiate them from veins. The majority of normal eye show a submacular first-order artery running horizontally toward the temporal periphery. These results will pave the way for a better knowledge of diseases affecting the choroidal circulation. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

ArteriesChoroidLaser Doppler holographyOCT

Identifiers

PMID40124308
PMCPMC11928843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.